Bioinspired surface hierarchical microstructures of Ti6Al4V alloy with a positive effect on osteoconduction
文献类型:期刊论文
作者 | Li, Chen2; Yang, Lijun2; Liu, Nan2; Yang, Yong1; Zhao, Jing5; Yang, Pengfei3; Cheng, Guanghua4 |
刊名 | Surface and Coatings Technology |
出版日期 | 2020-04-25 |
卷号 | 388 |
ISSN号 | 02578972 |
关键词 | Bioinspired hierarchical structures Osteoconduction Laser surface texturing Osteoblastic cell proliferation Cell adherence Ti6Al4V |
DOI | 10.1016/j.surfcoat.2020.125594 |
产权排序 | 2 |
英文摘要 | Osteoconduction is critical for the success of dental and orthopaedic implants. Inspired by the remarkable adhesion of the skin structures in tree frog toe pads, biomimetic hierarchical surface structures on titanium alloy implants are fabricated by laser surface texturing and chemistry surface treatment in this work, to improve osteoconduction on implants. The main differences in the wettability, bioactivity in simulated body fluid and osteoblastic cell MC3T3 proliferation were measured and analyzed among Ti6Al4V samples with smooth surface, micro-hexagons and hierarchical structures, respectively. Noteworthy, bioinspired hierarchical structures displayed the lowest contact angle in hydrophilicity, best bioactivity and excellent cell proliferation. The reasons for these differences were found and discussed in the topographical cues and bioactive surface layer. An innovative functionalization strategy of improving the osteoconduction on titanium alloy implants was proposed using the hierarchical structures, which is meaningful in various tissue engineering applications and implant fields. © 2020 Elsevier B.V. |
语种 | 英语 |
出版者 | Elsevier B.V. |
源URL | [http://ir.opt.ac.cn/handle/181661/93312] |
专题 | 西安光学精密机械研究所_瞬态光学技术国家重点实验室 |
通讯作者 | Li, Chen |
作者单位 | 1.State Key Laboratory of Transient Optics and Photonics, Xi'an Institute of Optics and Precision Mechanics, CAS, Xi'an; 710119, China; 2.College of Mechanical and Electrical Engineering, Shaanxi University of Science and Technology, Xi'an; 710021, China; 3.Key Laboratory of Space Radiobiology of Gansu Province, Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Institute of Modern Physics, CAS, Lanzhou; 730000, China; 4.School of Electronics and Information, Northwestern Polytechnical University, Xi'an; 710072, China 5.Shaanxi Province Geriatric Hospital, Xi'an; 710005, China; |
推荐引用方式 GB/T 7714 | Li, Chen,Yang, Lijun,Liu, Nan,et al. Bioinspired surface hierarchical microstructures of Ti6Al4V alloy with a positive effect on osteoconduction[J]. Surface and Coatings Technology,2020,388. |
APA | Li, Chen.,Yang, Lijun.,Liu, Nan.,Yang, Yong.,Zhao, Jing.,...&Cheng, Guanghua.(2020).Bioinspired surface hierarchical microstructures of Ti6Al4V alloy with a positive effect on osteoconduction.Surface and Coatings Technology,388. |
MLA | Li, Chen,et al."Bioinspired surface hierarchical microstructures of Ti6Al4V alloy with a positive effect on osteoconduction".Surface and Coatings Technology 388(2020). |
入库方式: OAI收割
来源:西安光学精密机械研究所
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