Improving timing performance of double-ended readout in TOF-PET detectors
文献类型：期刊论文
| 作者 | Guo, L.1,2,3,4; Tian, J.1,3; Chen, P.1,3 ; Derenzo, S.E.4; Choong, W.-S.4
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| 刊名 | Journal of Instrumentation
 |
| 出版日期 | 2020-01-02 |
| 卷号 | 15期号:1 |
| 关键词 | Gamma camera SPECT PET PET/CT coronary CT angiography (CTA) Instrumentation for gamma-electron therapy |
| ISSN号 | 17480221 |
| DOI | 10.1088/1748-0221/15/01/P01003 |
| 产权排序 | 1 |
| 英文摘要 | Scintillation crystals of 20 mm length or longer are needed for clinical time-of-flight positron emission tomography (TOF-PET) to ensure effective detection efficiency for gamma photons. However, the use of long crystals would deteriorate the key performance of TOF-PET detectors, time and spatial resolution, because of the variations in the travel times of the photons in crystals and the effects of parallax errors. In this work, we studied double-ended readout TOF-PET detectors based on coupling a long scintillation crystal to SiPMs at both ends for correcting the depth-dependent effects to improve the coincidence time resolution (CTR). In particular, we focused our attention to analyze timing performance using different correction methods, including trigger times of the individual photodetectors at both ends of the crystal, the simple average of the trigger times, and the weighted average based on the inverse variances of the depth-dependent corrected trigger times. For a 3 mm × 3 mm × 25 mm unpolished lutetium fine silicate (LFS) crystal with double-ended readout and practical head-on irradiation, a CTR of 246 ps FWHM can be achieved using depth-dependent timing-correction and weighted average time method compared to 280 ps FWHM using the conventional simple average time method and 393 ps FWHM using the conventional single-ended readout. The results show that the depth-dependent timing-correction and weighted average time method in double-ended readout can effectively correct for the trigger time variations in TOF-PET detector utilizing long unpolished crystals, resulting in an improvement in the CTR of as much as 37% compared to single-ended readout. © 2020 IOP Publishing Ltd and Sissa Medialab. |
| 语种 | 英语 |
| 出版者 | Institute of Physics Publishing |
| 源URL | [http://ir.opt.ac.cn/handle/181661/93324]  |
| 专题 | 条纹相机工程中心 |
| 作者单位 | 1.Collaborative Innovation Center of Extreme Optics, Shanxi University, No. 92 Wucheng Road, Taiyuan; 030006, China 2.College of Materials Science and Opto-Electronic Technology, University of Chinese Academy of Sciences, No. 19 Yuquan Road, Beijing; 100049, China; 3.Key Laboratory of Ultra-fast Photoelectric Diagnostics Technology, Xi'An Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, No. 17 Xinxi Road, Xi'an; 710119, China; 4.Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley; CA; 94720, United States; |
| 推荐引用方式 GB/T 7714 | Guo, L.,Tian, J.,Chen, P.,et al. Improving timing performance of double-ended readout in TOF-PET detectors[J]. Journal of Instrumentation,2020,15(1). |
| APA | Guo, L.,Tian, J.,Chen, P.,Derenzo, S.E.,&Choong, W.-S..(2020).Improving timing performance of double-ended readout in TOF-PET detectors.Journal of Instrumentation,15(1). |
| MLA | Guo, L.,et al."Improving timing performance of double-ended readout in TOF-PET detectors".Journal of Instrumentation 15.1(2020). |
入库方式： OAI收割
来源：西安光学精密机械研究所
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