Antibacterial metabolites from Ascidian-derived fungus Aspergillus clavatus AS-107
文献类型：期刊论文
| 作者 | Song, Qi1,2,4 ; Li, Xiao-Ming1,2,3; Hu, Xue-Yi1,2; Li, Xin1,2,3; Chi, Lu-Ping1,2,4; Li, Hong-Lei1,2,3; Wang, Bin-Gui1,2,3
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| 刊名 | PHYTOCHEMISTRY LETTERS
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| 出版日期 | 2019-12-01 |
| 卷号 | 34页码:30-34 |
| 关键词 | Ascidian-derived fungus Aspergillus clavatus Secondary metabolites Antibacterial activity |
| ISSN号 | 1874-3900 |
| DOI | 10.1016/j.phytol.2019.09.004 |
| 通讯作者 | Wang, Bin-Gui(wangbg@ms.qdio.ac.cn) |
| 英文摘要 | Six secondary metabolites including a new aminobenzoic peptide seco-clavatustide B (1) and a new clavatoic acid derivative 5-acetyl-2,4-dihydroxy-3-methylbenzoic acid (3), were characterized from the EtOAc extracts of the Ascidian-derived endophytic fungus Aspergillus clavatus AS-107. The absolute configuration of compound 1 was established by electronic circular dichroism quantum calculation and the structure of compound 3 was elucidated on the basis of spectroscopic data together with single-crystal X-ray diffraction experiment. The isolated compounds were tested for antimicrobial activities against human and aquatic pathogenic bacteria. Compounds 1 and 2 showed potent activity against aquatic pathogens Aeromonas hydrophilia and Pseudomonas aeruginosa with MIC values of 8.2 and 8.8 mu M, respectively. |
| 资助项目 | NSFC-Shandong Joint Fund for Marine Science Research Centers[U1606403] ; Taishan Scholar Project from Shandong Province of China |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000498702200006 |
| 出版者 | ELSEVIER |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/163807]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Wang, Bin-Gui |
| 作者单位 | 1.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Nanhai Rd 7, Qingdao 266071, Shandong, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Shandong, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Megasci, Nanhai Rd 7, Qingdao 266071, Shandong, Peoples R China 4.Univ Chinese Acad Sci, Yuquan Rd 19A, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Song, Qi,Li, Xiao-Ming,Hu, Xue-Yi,et al. Antibacterial metabolites from Ascidian-derived fungus Aspergillus clavatus AS-107[J]. PHYTOCHEMISTRY LETTERS,2019,34:30-34. |
| APA | Song, Qi.,Li, Xiao-Ming.,Hu, Xue-Yi.,Li, Xin.,Chi, Lu-Ping.,...&Wang, Bin-Gui.(2019).Antibacterial metabolites from Ascidian-derived fungus Aspergillus clavatus AS-107.PHYTOCHEMISTRY LETTERS,34,30-34. |
| MLA | Song, Qi,et al."Antibacterial metabolites from Ascidian-derived fungus Aspergillus clavatus AS-107".PHYTOCHEMISTRY LETTERS 34(2019):30-34. |
入库方式： OAI收割
来源：海洋研究所
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