bHLH genes polymorphisms and their association with growth traits in the Pacific oyster Crassostrea gigas
文献类型：期刊论文
| 作者 | Chen Na2,3; Li Li1; Li Chenghua2; Lin Zhihua3; Meng Jie1 ; Liu Sheng1; Song Kai1; Bao Yongbo3
|
| 刊名 | JOURNAL OF OCEANOLOGY AND LIMNOLOGY
 |
| 出版日期 | 2019-12-05 |
| 页码 | 7 |
| 关键词 | Crassostrea gigas basic helix-loop-helix (bHLH) re-sequencing single nucleotide polymorphism (SNP) shot growth traits |
| ISSN号 | 2096-5508 |
| DOI | 10.1007/s00343-019-9070-4 |
| 通讯作者 | Bao Yongbo(bobbao2001@gmail.com) |
| 英文摘要 | The basic helix-loop-helix (bHLH) genes encode a large superfamily of transcription factors in the Pacific oyster (Crassostrea gigas), and play a very important role in regulation of growth and development. To investigate the oyster growth traits and the associations with bHLH genes variations, we analyzed the gene polymorphisms-traits association in a wild population, and confirmed the results in another independent wild population by targeted gene re-sequencing and SNPshot analysis. After screening the single nucleotide polymorphisms (SNPs) in three candidate genes of the bHLH family (88 bHLH genes in two wild oyster populations in total), we identified the allele CgLoblHLH4-T/G located in the exon of the CgLoblHLH4 gene. This allele is a non-synonymous mutation (Phe/Leu) with an extremely significant association with shell width (P<0.01) and allele G is beneficial to shell width. This SNP on the CgLoblHLH4 gene might have a potential value as a genetic marker of growth traits that could be used in breeding in C. gigas in the future. |
| 资助项目 | National Key R&D Program of China[2018YFD0901400] ; National Natural Science Foundation of China[31672678] ; Ningbo Municipal Science and Technology International Cooperation Research Projects[2016D10017] ; Zhejiang Provincial Major Program of Science and Technology[2016C02055-9] |
| WOS研究方向 | Marine & Freshwater Biology ; Oceanography |
| 语种 | 英语 |
| WOS记录号 | WOS:000500871700004 |
| 出版者 | SCIENCE PRESS |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/163852]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Bao Yongbo |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Shandong, Peoples R China 2.Ningbo Univ, Sch Marine Sci, Ningbo 315211, Zhejiang, Peoples R China 3.Zhejiang Wanli Univ, Coll Biol & Environm Sci, Zhejiang Key Lab Aquat Germplasm Resources, Ningbo 315121, Zhejiang, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen Na,Li Li,Li Chenghua,et al. bHLH genes polymorphisms and their association with growth traits in the Pacific oyster Crassostrea gigas[J]. JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2019:7. |
| APA | Chen Na.,Li Li.,Li Chenghua.,Lin Zhihua.,Meng Jie.,...&Bao Yongbo.(2019).bHLH genes polymorphisms and their association with growth traits in the Pacific oyster Crassostrea gigas.JOURNAL OF OCEANOLOGY AND LIMNOLOGY,7. |
| MLA | Chen Na,et al."bHLH genes polymorphisms and their association with growth traits in the Pacific oyster Crassostrea gigas".JOURNAL OF OCEANOLOGY AND LIMNOLOGY (2019):7. |
入库方式： OAI收割
来源：海洋研究所
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