Dorsoventral decoupling of Hox gene expression underpins the diversification of molluscs
文献类型：期刊论文
| 作者 | Huan, Pin1,2,3 ; Wang, Qian1,3; Tan, Sujian3; Liu, Baozhong1,2,3
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| 刊名 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
 |
| 出版日期 | 2020-01-07 |
| 卷号 | 117期号:1页码:503-512 |
| 关键词 | Hox mollusc dorsoventral decoupling staggered expression shell |
| ISSN号 | 0027-8424 |
| DOI | 10.1073/pnas.1907328117 |
| 通讯作者 | Liu, Baozhong(bzliu@qdio.ac.cn) |
| 英文摘要 | In contrast to the Hox genes in arthropods and vertebrates, those in molluscs show diverse expression patterns with differences reported among lineages. Here, we investigate 2 phylogenetically distant molluscs, a gastropod and a polyplacophoran, and show that the Hox expression in both species can be divided into 2 categories. The Hox expression in the ventral ectoderm generally shows a canonical staggered pattern comparable to the patterns of other bilaterians and likely contributes to ventral patterning, such as neurogenesis. The other category of Hox expression on the dorsal side is strongly correlated with shell formation and exhibits lineage-specific characteristics in each class of mollusc. This generalized model of decoupled dorsoventral Hox expression is compatible with known Hox expression data from other molluscan lineages and may represent a key characteristic of molluscan Hox expression. These results support the concept of widespread staggered Hox expression in Mollusca and reveal aspects that may be related to the evolutionary diversification of molluscs. We propose that dorsoventral decoupling of Hox expression allowed lineage-specific dorsal and ventral patterning, which may have facilitated the evolution of diverse body plans in different molluscan lineages. |
| 资助项目 | National Key Research & Development Program of China[2018YFD0900104] ; Marine Science & Technology Fund of Shandong Province for Pilot National Laboratory for Marine Science and Technology (Qingdao)[2018SDKJ03021] ; China Agriculture Research System[CARS-49] ; National Natural Science Foundation of China[41776157] |
| WOS研究方向 | Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:000506001200073 |
| 出版者 | NATL ACAD SCIENCES |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/164148]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Liu, Baozhong |
| 作者单位 | 1.Univ Chinese Acad Sci, Coll Adv Agr Sci, Beijing 100039, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266000, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huan, Pin,Wang, Qian,Tan, Sujian,et al. Dorsoventral decoupling of Hox gene expression underpins the diversification of molluscs[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2020,117(1):503-512. |
| APA | Huan, Pin,Wang, Qian,Tan, Sujian,&Liu, Baozhong.(2020).Dorsoventral decoupling of Hox gene expression underpins the diversification of molluscs.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,117(1),503-512. |
| MLA | Huan, Pin,et al."Dorsoventral decoupling of Hox gene expression underpins the diversification of molluscs".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117.1(2020):503-512. |
入库方式： OAI收割
来源：海洋研究所
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