中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 烟台海岸带研究所
  3. 中国科学院烟台海岸带研究所
  4. 中科院海岸带环境过程与生态修复重点实验室
  5. 近岸生态与环境实验室
Potentiometric aptasensing of small molecules based on surface charge change

文献类型：期刊论文

作者Lv, Enguang; Ding, Jiawang; Qin, Wei
刊名SENSORS AND ACTUATORS B-CHEMICAL
出版日期2018-04-15
卷号259页码:463-466
关键词Aptasensor Bisphenol A Potentiometry Surface charge Solid state
ISSN号0925-4005
DOI10.1016/j.snb.2017.12.067
产权排序[Lv, Enguang ; Ding, Jiawang ; Qin, Wei] Chinese Acad Sci, Shandong Prov Key Lab Coastal Environm Proc, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China ; [Lv, Enguang] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
文献子类Article
英文摘要Solid-state potentiometric sensors based on surface charge change are well-established tools for measuring ions and biological species. However, their use for detection of small molecules with high sensitivity and good selectivity is still elusive. In this work, a novel potentiometric aptasensing platform for small molecules is presented, using bisphenol A (BPA) as a model. The proposed sensor can be prepared by layer-by-layer assembling of carboxylated multiwall carbon nanotubes, poly(diallyldimethylammonium chloride) (polycation), and aptamer (polyanion) on the electrode surface. The presence of BPA induces the conformational change and detachment of the aptamer at the surface of the modified electrode, which leads to a variation of the surface charge (negative to positive) and therefore a potential change. The introduction of polyions can cause substantial charge change on the electrode surface, thus improving the sensitivity of the sensor. The morphology and electron-transfer properties of the electrode have been characterized. Under optimum conditions, the present sensor shows a stable response to BPA in the concentration range from 3.2 x 10(-8) to 1.0 x 10(-6) M with a detection limit of 1.0 x 10(-8) M. The proposed methodology can be used for sensitive potentiometric sensing of other small molecules involved in aptamer/target binding events. (C) 2017 Elsevier B.V. All rights reserved.
WOS关键词ION-SELECTIVE ELECTRODES ; MEMBRANE ELECTRODES ; BISPHENOL-A ; SENSORS ; GOLD ; COPPER(II) ; ADSORPTION ; FILMS
WOS研究方向Chemistry ; Electrochemistry ; Instruments & Instrumentation
语种英语
WOS记录号WOS:000424877600055
资助机构National Natural Science Foundation of China [21575158, 21475148] ; National Key Research and Development Program of China [2016YFC1400700] ; Instrument Developing Project of the Chinese Academy of Sciences [Y728021021] ; CAS Youth Innovation Promotion Association [2014190] ; Taishan Scholar Program of Shandong Province [TS20081159]
源URL[http://ir.yic.ac.cn/handle/133337/24375]  
专题烟台海岸带研究所_近岸生态与环境实验室
烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
作者单位1.Chinese Acad Sci, Shandong Prov Key Lab Coastal Environm Proc, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China;
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714		 Lv, Enguang,Ding, Jiawang,Qin, Wei. Potentiometric aptasensing of small molecules based on surface charge change[J]. SENSORS AND ACTUATORS B-CHEMICAL,2018,259:463-466.
APA Lv, Enguang,Ding, Jiawang,&Qin, Wei.(2018).Potentiometric aptasensing of small molecules based on surface charge change.SENSORS AND ACTUATORS B-CHEMICAL,259,463-466.
MLA Lv, Enguang,et al."Potentiometric aptasensing of small molecules based on surface charge change".SENSORS AND ACTUATORS B-CHEMICAL 259(2018):463-466.

入库方式： OAI收割

来源：烟台海岸带研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。