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Strategies of molecular imprinting-based fluorescence sensors for chemical and biological analysis
文献类型：期刊论文
| 作者 | Yang, Qian; Li, Jinhua ; Wang, Xiaoyan; Peng, Hailong; Xiong, Hua; Chen, Lingxin
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| 刊名 | BIOSENSORS & BIOELECTRONICS
 |
| 出版日期 | 2018-07-30 |
| 卷号 | 112页码:54-71 |
| 关键词 | Molecular imprinting Sensor Fluorescent detection Construction strategy Microdevice |
| ISSN号 | 0956-5663 |
| DOI | 10.1016/j.bios.2018.04.028 |
| 产权排序 | [Yang, Qian ; Peng, Hailong ; Xiong, Hua] Nanchang Univ, State Key Lab Food Sci & Technol, Nanchang 330047, Jiangxi, Peoples R China ; [Yang, Qian ; Li, Jinhua ; Wang, Xiaoyan ; Chen, Lingxin] Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China ; [Yang, Qian ; Li, Jinhua ; Wang, Xiaoyan ; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, Yantai 264003, Peoples R China ; [Wang, Xiaoyan] Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China |
| 文献子类 | Article |
| 英文摘要 | One pressing concern today is to construct sensors that can withstand various disturbances for highly selective and sensitive detecting trace analytes in complicated samples. Molecularly imprinted polymers (MIPs) with tailor-made binding sites are preferred to be recognition elements in sensors for effective targets detection, and fluorescence measurement assists in highly sensitive detection and user-friendly control. Accordingly, molecular imprinting-based fluorescence sensors (MI-FL sensors) have attracted great research interest in many fields such as chemical and biological analysis. Herein, we comprehensively review the recent advances in MI-FL sensors construction and applications, giving insights on sensing principles and signal transduction mechanisms, focusing on general construction strategies for intrinsically fluorescent or nonfluorescent analytes and improvement strategies in sensing performance, particularly in sensitivity. Construction strategies are well overviewed, mainly including the traditional indirect methods of competitive binding against pre-bound fluorescent indicators, employment of fluorescent functional monomers and embedding of fluorescence substances, and novel rational designs of hierarchical architecture (core-shell/hollow and mesoporous structures), post-imprinting modification, and ratiometric fluorescence detection. Furthermore, MI-FL sensor based microdevices are discussed, involving micromotors, test strips and microfluidics, which are more portable for rapid point-of-care detection and in-field diagnosing. Finally, the current challenges and future perspectives of MI-FL sensors are proposed. |
| WOS关键词 | GRAPHENE QUANTUM DOTS ; METAL-ORGANIC FRAMEWORKS ; CORE-SHELL PARTICLES ; ONE-POT SYNTHESIS ; UP-CONVERSION ; RATIOMETRIC FLUORESCENCE ; SENSITIVE DETECTION ; SELECTIVE DETECTION ; BISPHENOL-A ; POLYMER NANOPARTICLES |
| WOS研究方向 | Biophysics ; Biotechnology & Applied Microbiology ; Chemistry, Analytical ; Electrochemistry ; Nanoscience & Nanotechnology |
| 语种 | 英语 |
| WOS记录号 | WOS:000433648000008 |
| 资助机构 | National Natural Science Foundation of China [21667018, 21477160, 31660482, 41776110, 21575159] ; Natural Science Foundation of Shandong Province of China [ZR2016BL25] |
| 源URL | [http://ir.yic.ac.cn/handle/133337/24433]  |
| 专题 | 烟台海岸带研究所_近岸生态与环境实验室 烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室 |
| 作者单位 | 1.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China 2.Nanchang Univ, State Key Lab Food Sci & Technol, Nanchang 330047, Jiangxi, Peoples R China; 3.Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; 4.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, Yantai 264003, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Yang, Qian,Li, Jinhua,Wang, Xiaoyan,et al. Strategies of molecular imprinting-based fluorescence sensors for chemical and biological analysis[J]. BIOSENSORS & BIOELECTRONICS,2018,112:54-71. |
| APA | Yang, Qian,Li, Jinhua,Wang, Xiaoyan,Peng, Hailong,Xiong, Hua,&Chen, Lingxin.(2018).Strategies of molecular imprinting-based fluorescence sensors for chemical and biological analysis.BIOSENSORS & BIOELECTRONICS,112,54-71. |
| MLA | Yang, Qian,et al."Strategies of molecular imprinting-based fluorescence sensors for chemical and biological analysis".BIOSENSORS & BIOELECTRONICS 112(2018):54-71. |
入库方式： OAI收割
来源：烟台海岸带研究所
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