The impact of ocean acidification and cadmium on the immune responses of Pacific oyster, Crassostrea gigas
文献类型：期刊论文
| 作者 | Cao, Ruiwen; Liu, Yongliang; Wang, Qing ; Zhang, Qianqian; Yang, Dinglong; Liu, Hui; Qu, Yi; Zhao, Jianmin
|
| 刊名 | FISH & SHELLFISH IMMUNOLOGY
 |
| 出版日期 | 2018-10 |
| 卷号 | 81页码:456-462 |
| 关键词 | Ocean acidification Cadmium Crassostrea gigas Immune response |
| ISSN号 | 1050-4648 |
| DOI | 10.1016/j.fsi.2018.07.055 |
| 产权排序 | [Cao, Ruiwen ; Liu, Yongliang ; Wang, Qing ; Zhang, Qianqian ; Yang, Dinglong ; Liu, Hui ; Qu, Yi ; Zhao, Jianmin] Yantai Inst Coastal Zone Res, Muping Coastal Environm Res Stn, Yantai 264117, Shandong, Peoples R China ; [Cao, Ruiwen ; Wang, Qing ; Zhang, Qianqian ; Yang, Dinglong ; Liu, Hui ; Qu, Yi] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res & Dev Ctr Efficient Utilizat Coastal Bioresou, Yantai 264003, Shandong, Peoples R China ; [Cao, Ruiwen ; Qu, Yi] Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 文献子类 | Article |
| 英文摘要 | Seawater acidification (OA) and cadmium (Cd) has the potential to lead to immunosuppression effect on marine bivalves. However, the interaction between these two environmental stressors on immune system of marine bivalves has received limited attention. In order to evaluate the defense responses of oysters under the combined exposure to OA and cadmium, the oysters Crassostrea gigas were exposed to 10 mu g/L Cd at three pH levels (8.1, 7.8 and 7.6) for 31 days. Results showed that OA exposure alone led to increased DNA damage, apoptosis rate and ROS production of hemocytes. However, inhibited phagocytosis rate, combined with increased DNA damage, apoptosis rate and ROS production of hemocytes were observed in oysters under exposure to Cd exposure alone or combined with OA. Significant interactive effects between OA and Cd were observed on ROS production and DNA damage of hemocytes. In addition, there is generally significant increase in the mRNA expression of genes related to immune-related TLR pathway and two immune factors (TNF and integrin beta-1B) in Cd-exposed oysters at pH 7.6. The results revealed that even though the mRNA expression of genes related to immune responses (TLR pathway and immune factors) was stimulated to counteract the immunosuppression caused by acidified seawater and Cd, depressed hemocyte function perhaps sensitized oysters to potential pathogen infection. |
| WOS关键词 | SOLUBLE ADENYLYL-CYCLASE ; SIGNALING PATHWAYS ; PHYSIOLOGICAL-RESPONSES ; MARINE-ENVIRONMENT ; TOXICITY ; STRESS ; APOPTOSIS ; SEAWATER ; WATER ; PH |
| WOS研究方向 | Fisheries ; Immunology ; Marine & Freshwater Biology ; Veterinary Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000443665900054 |
| 资助机构 | Chinese Academy of Sciences [XDA11020305, KZZDEW-14, YJKYYQ20170071] ; National Natural Science Foundation of China [31172388] ; Science and Technology Service Network Initiative (STS) Project [KFJ-STS-ZDTP-023] ; Youth Innovation Promotion Association, CAS [2016196] |
| 源URL | [http://ir.yic.ac.cn/handle/133337/24537]  |
| 专题 | 中国科学院牟平海岸带环境综合试验站 烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室 烟台海岸带研究所_近岸生态与环境实验室 海岸带生物资源高效利用研究与发展中心 |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res & Dev Ctr Efficient Utilizat Coastal Bioresou, Yantai 264003, Shandong, Peoples R China; 2.Yantai Inst Coastal Zone Res, Muping Coastal Environm Res Stn, Yantai 264117, Shandong, Peoples R China; 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cao, Ruiwen,Liu, Yongliang,Wang, Qing,et al. The impact of ocean acidification and cadmium on the immune responses of Pacific oyster, Crassostrea gigas[J]. FISH & SHELLFISH IMMUNOLOGY,2018,81:456-462. |
| APA | Cao, Ruiwen.,Liu, Yongliang.,Wang, Qing.,Zhang, Qianqian.,Yang, Dinglong.,...&Zhao, Jianmin.(2018).The impact of ocean acidification and cadmium on the immune responses of Pacific oyster, Crassostrea gigas.FISH & SHELLFISH IMMUNOLOGY,81,456-462. |
| MLA | Cao, Ruiwen,et al."The impact of ocean acidification and cadmium on the immune responses of Pacific oyster, Crassostrea gigas".FISH & SHELLFISH IMMUNOLOGY 81(2018):456-462. |
入库方式： OAI收割
来源：烟台海岸带研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。