Low cost fabrication of microfluidic paper-based analytical devices with water-based polyurethane acrylate and their application for bacterial detection
文献类型：期刊论文
| 作者 | Lin, D; Li, BW ; Qi, J; Ji, XF; Yang, SX; Wang, WH; Chen, LX
|
| 刊名 | SENSORS AND ACTUATORS B-CHEMICAL
 |
| 出版日期 | 2020-01-15 |
| 卷号 | 303页码:127213 |
| 关键词 | Paper microfluidics muPAD Polyurethane acrylate Ultraviolet light curing Bacterial detection |
| DOI | 10.1016/j.snb.2019.127213 |
| 产权排序 | [Lin, Dong ; Li, Bowei ; Qi, Ji ; Yang, Shixuan ; Wang, Wenhai ; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China ; [Lin, Dong ; Ji, Xiaofei ; Chen, Lingxin] Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China ; [Chen, Lingxin] Pilot Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Shandong, Peoples R China ; [Li, Bowei] Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Shandong, Peoples R China |
| 文献子类 | Article |
| 英文摘要 | This study presents a simple, inexpensive and environment-friendly fabrication strategy for microfluidic paper-based analytical devices which can resist the penetration of surfactant solutions and organic solvents, by using water-based polyurethane acrylate via UV light curing. The filter paper's barrier created using cured PUA could withstand surfactant solutions (10 wt%, CTAB, SDS and Triton X-100) and organic solvents (methanol, isopropanol, DMF, DMSO, etc). This is very useful for analyzing complicated biological samples on the microfluidic paper-based analytical devices. In addition, the expense of water-based polyurethane acrylate is very cheap (about $8/500 g) and PUA developer is water that is environmental-friendly. To further verify its advantage, we successfully demonstrated the proposed microfluidic devices for detection of E. coli targets in tap water and seawater via colorimetric analysis in a fast and convenient manner. Our results revealed that the linear response to E. coli BL21 was in the range of 10(4)similar to 10(9) cfu/mL. The proposed method can effectively avoid the damage for the hydrophobic barriers from the solution even some aggressive liquids, and shows great potential in on-site analysis, environmental monitoring, and food safety. |
| WOS关键词 | FLUORESCENCE DETECTION ; INK-JET ; WAX ; BARRIERS ; CHIP ; ION |
| WOS研究方向 | Chemistry, Analytical ; Electrochemistry ; Instruments & Instrumentation |
| 语种 | 英语 |
| WOS记录号 | WOS:000500370900005 |
| 资助机构 | National Key Research and Development Program of China [2016YFC1400702] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [41776110, 21976209, 21876199] ; Shandong Provincial Medicine and Health Technology Development Plan [2017WSB290215] ; Science and Technology Development Plan of Yantai [2017ZH089] ; Department of Science and Technology of Shandong Province of China [GG201709290055, 2017ZH093] ; Taishan Scholar Project Special Funding |
| 源URL | [http://ir.yic.ac.cn/handle/133337/24769]  |
| 专题 | 烟台海岸带研究所_山东省海岸带环境工程技术研究中心 烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室 |
| 作者单位 | 1.Pilot Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Shandong, Peoples R China; 2.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Shandong, Peoples R China 3.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China; 4.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Lin, D,Li, BW,Qi, J,et al. Low cost fabrication of microfluidic paper-based analytical devices with water-based polyurethane acrylate and their application for bacterial detection[J]. SENSORS AND ACTUATORS B-CHEMICAL,2020,303:127213. |
| APA | Lin, D.,Li, BW.,Qi, J.,Ji, XF.,Yang, SX.,...&Chen, LX.(2020).Low cost fabrication of microfluidic paper-based analytical devices with water-based polyurethane acrylate and their application for bacterial detection.SENSORS AND ACTUATORS B-CHEMICAL,303,127213. |
| MLA | Lin, D,et al."Low cost fabrication of microfluidic paper-based analytical devices with water-based polyurethane acrylate and their application for bacterial detection".SENSORS AND ACTUATORS B-CHEMICAL 303(2020):127213. |
入库方式： OAI收割
来源：烟台海岸带研究所
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