Radiation-induced intestinal damage: latest molecular and clinical developments
文献类型：期刊论文
| 作者 | Lu, LN; Li, WJ ; Chen, LH; Su, Q; Wang, YB; Guo, Z; Lu, YJ; Liu, B; Qin, S
|
| 刊名 | FUTURE ONCOLOGY
 |
| 出版日期 | 2019-12 |
| 卷号 | 15期号:35页码:4105-4118 |
| 关键词 | cancer intestinal damage ionizing radiation radiation enteritis radiation enteropathy |
| ISSN号 | 1479-6694 |
| DOI | 10.2217/fon-2019-0416 |
| 产权排序 | [Lu, Lina ; Liu, Bin] Lanzhou Univ, Sch Nucl Sci & Technol, Lanzhou 730000, Gansu, Peoples R China ; [Li, Wenjun ; Qin, Song] Chinese Acad Sci, Yantai Inst Costal Zone Res, Key Lab Biol & Bioresource Utilizat, Yantai 264003, Peoples R China ; [Lu, Lina ; Chen, Lihua ; Su, Qiong ; Wang, Yanbin ; Lu, Yongjuan] Northwest Minzu Univ, Sch Chem Engn, Lanzhou 730000, Gansu, Peoples R China ; [Li, Wenjun ; Qin, Song] Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Shandong, Peoples R China ; [Guo, Zhong] Northwest Minzu Univ, Med Coll, Lanzhou 730000, Gansu, Peoples R China ; [Liu, Bin] Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Gansu, Peoples R China |
| 文献子类 | Review |
| 英文摘要 | Aim: To systematically review the prophylactic and therapeutic interventions for reducing the incidence or severity of intestinal symptoms among cancer patients receiving radiotherapy. Materials & methods: A literature search was conducted in the PubMed database using various search terms, including 'radiation enteritis', 'radiation enteropathy', 'radiation-induced intestinal disease', 'radiation-induced intestinal damage' and 'radiation mucositis'. The search was limited to in vivo studies, clinical trials and meta-analyses published in English with no limitation on publication date. Other relevant literature was identified based on the reference lists of selected studies. Results: The pathogenesis of acute and chronic radiation-induced intestinal damage as well as the prevention and treatment approaches were reviewed. Conclusion: There is inadequate evidence to strongly support the use of a particular strategy to reduce radiation-induced intestinal damage. More high-quality randomized controlled trials are required for interventions with limited evidence suggestive of potential benefits. |
| WOS关键词 | RAT SMALL-INTESTINE ; STEM-CELLS ; IONIZING-RADIATION ; GASTROINTESTINAL TOXICITY ; INDUCED APOPTOSIS ; STROMAL CELLS ; UP-REGULATION ; SMALL-BOWEL ; INJURY ; RADIOTHERAPY |
| WOS研究方向 | Oncology |
| 语种 | 英语 |
| WOS记录号 | WOS:000502552400010 |
| 资助机构 | National Key Research and Development Program of China [2018YFD0901102] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81560508, 51563022, 51562033] ; Northwest Minzu University's Double First-class and Characteristic Development Guide Special Funds-Chemistry Key Disciplines in Gansu Province [11080316] |
| 源URL | [http://ir.yic.ac.cn/handle/133337/24801]  |
| 专题 | 烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Costal Zone Res, Key Lab Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; 2.Northwest Minzu Univ, Sch Chem Engn, Lanzhou 730000, Gansu, Peoples R China; 3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Shandong, Peoples R China; 4.Northwest Minzu Univ, Med Coll, Lanzhou 730000, Gansu, Peoples R China; 5.Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Gansu, Peoples R China 6.Lanzhou Univ, Sch Nucl Sci & Technol, Lanzhou 730000, Gansu, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Lu, LN,Li, WJ,Chen, LH,et al. Radiation-induced intestinal damage: latest molecular and clinical developments[J]. FUTURE ONCOLOGY,2019,15(35):4105-4118. |
| APA | Lu, LN.,Li, WJ.,Chen, LH.,Su, Q.,Wang, YB.,...&Qin, S.(2019).Radiation-induced intestinal damage: latest molecular and clinical developments.FUTURE ONCOLOGY,15(35),4105-4118. |
| MLA | Lu, LN,et al."Radiation-induced intestinal damage: latest molecular and clinical developments".FUTURE ONCOLOGY 15.35(2019):4105-4118. |
入库方式： OAI收割
来源：烟台海岸带研究所
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