Synthesis of Quaternary Ammonium Salts of Chitosan Bearing Halogenated Acetate for Antifungal and Antibacterial Activities
文献类型：期刊论文
| 作者 | Zhang, Jingjing; Tan, Wenqiang ; Luan, Fang; Yin, Xiuli; Dong, Fang; Li, Qing; Guo, Zhanyong
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| 刊名 | POLYMERS
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| 出版日期 | 2018-05 |
| 卷号 | 10期号:5页码:530 |
| 关键词 | quaternary ammonium salts of chitosan halogenated acetate characterization antifungal activity antibacterial activity |
| ISSN号 | 2073-4360 |
| DOI | 10.3390/polym10050530 |
| 产权排序 | [Zhang, Jingjing ; Tan, Wenqiang ; Luan, Fang ; Yin, Xiuli ; Dong, Fang ; Li, Qing ; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China ; [Zhang, Jingjing ; Tan, Wenqiang ; Luan, Fang ; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 文献子类 | Article |
| 英文摘要 | In this paper, quaternary ammonium salts of chitosan bearing halogenated acetate, including N,N,N-trimethyl chitosan chloroacetate (TMCSC), N,N,N-trimethyl chitosan dichloroacetate (TMCSDC), N,N,N-trimethyl chitosan trichloroacetate (TMCSTC), and N,N,N-trimethyl chitosan trifluoroacetate (TMCSTF), were prepared via N,N,N-trimethyl chitosan iodide (TMCSI). The obtained chitosan derivatives were characterized by FT-IR, H-1 NMR spectra, C-13 NMR spectra, and elemental analysis. Their antifungal property against Fusarium oxysporum f. sp. cucumebrium Owen (F. oxysporum f. sp. cucumebrium Owen), Botrytis cinerea (B. cinerea), and Phomopsis asparagi (P. asparagi) were evaluated by hyphal measurement method at concentrations ranging from 0.08 mg/mL to 0.8 mg/mL. Meanwhile, two common bacteria, Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), were selected as the model Gram-negative and Gram-positive bacteria to evaluate the antibacterial property of the chitosan derivatives by agar well diffusion method. The results showed that TMCSC, TMCSDC, TMCSTC, and TMCSTF had better antifungal and antibacterial activities than chitosan and TMCSI. In particular, a rule showed that the inhibitory activity decreased in the order: TMCSTF > TMCSTC > TMCSDC > TMCSC > TMCSI > chitosan, which was consistent with the electron-withdrawing property of different halogenated acetate. Apparently, the quaternary ammonium salts of chitosan with stronger electron withdrawing ability possessed relatively greater antifungal and antibacterial activities. This experiment provides a potentially feasible method for the further utilization of chitosan in fields of antifungal and antibacterial biomaterials. |
| WOS关键词 | ANTIMICROBIAL ACTIVITY ; DERIVATIVES ; PROPERTY ; NANOPARTICLES ; CONJUGATION ; HYDROGELS |
| WOS研究方向 | Polymer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000435199300068 |
| 资助机构 | National Natural Science Foundation of China [41576156] ; Natural Science Foundation of Shandong Province of China [ZR2017BD015] ; Yantai Science and Technology Development Plan [2015ZH078] ; Technology Research Funds Projects of Ocean [2015418022-3] |
| 源URL | [http://ir.yic.ac.cn/handle/133337/24470]  |
| 专题 | 海岸带生物资源高效利用研究与发展中心 烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室 烟台海岸带研究所_污染过程与控制实验室 |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Zhang, Jingjing,Tan, Wenqiang,Luan, Fang,et al. Synthesis of Quaternary Ammonium Salts of Chitosan Bearing Halogenated Acetate for Antifungal and Antibacterial Activities[J]. POLYMERS,2018,10(5):530. |
| APA | Zhang, Jingjing.,Tan, Wenqiang.,Luan, Fang.,Yin, Xiuli.,Dong, Fang.,...&Guo, Zhanyong.(2018).Synthesis of Quaternary Ammonium Salts of Chitosan Bearing Halogenated Acetate for Antifungal and Antibacterial Activities.POLYMERS,10(5),530. |
| MLA | Zhang, Jingjing,et al."Synthesis of Quaternary Ammonium Salts of Chitosan Bearing Halogenated Acetate for Antifungal and Antibacterial Activities".POLYMERS 10.5(2018):530. |
入库方式： OAI收割
来源：烟台海岸带研究所
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