The antioxidant and antifungal activity of chitosan derivatives bearing Schiff bases and quaternary ammonium salts
文献类型：期刊论文
| 作者 | Wei, LJ; Tan, WQ ; Wang, G; Li, Q; Dong, F; Guo, ZY
|
| 刊名 | CARBOHYDRATE POLYMERS
 |
| 出版日期 | 2019-12-15 |
| 卷号 | 226页码:UNSP 115256 |
| 关键词 | Chitosan Schiff bases Quaternary ammonium salts Antifungal activity Antioxidant activity |
| ISSN号 | 0144-8617 |
| DOI | 10.1016/j.carbpol.2019.115256 |
| 产权排序 | [Wei, Lijie ; Tan, Wenqiang ; Wang, Gang ; Li, Qing ; Dong, Fang ; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China ; [Wei, Lijie ; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 文献子类 | Article |
| 英文摘要 | In order to improve the antioxidant and antifungal activity of chitosan, eight chitosan derivatives containing Schiff bases and quaternary ammonium salts were synthesized via an intermediate 6-O-chloroacetyl-2-N,N,N-trimethyl quaternary ammonium salt chitosan. Detailed structural characterization was carried out using FTIR and H-1 NMR spectroscopy, and elemental analysis. The antifungal activity against F. oxysporum f sp. cucumerium, B. cinerea, and F. oxysponim f sp. niveum was evaluated using a mycelium growth rate test. The results indicated that the chitosan derivatives exhibited enhanced antifungal activity when compared to chitosan, especially at 1.0 mg/mL. 644-(2,3-dihydroxyl-benzimide) pyridine] acetyl-2-N,N,N-trimethyl-chitosan chloride (2.3HBPATC), 6-[4-(2,3,4-trihydroxyl-benzimide) pyridine] acetyl-2-N,N,N-trimethyl-chitosan chloride (2.3.4HBPATC), 6-[4-(2-fluorine-benzimide) pyridine] acetyl-2-N,N,N-trimethyl-chitosan chloride (FBPATC), 644-(2-chlorine-benzimide) pyridine] acetyl-2-N,N,N-trimethyl-chitosan chloride (CBPATC), 6-[4-(2-bromine-benzimide) pyridine] acetyl-2-N,N,N-trimethyl-chitosan chloride (BBPATC), and 644-(2-hydroxyl-4-chlorine-benzimide) pyridine] acetyl-2-N,N,N-trimethyl-chitosan chloride (HCBPATC) showed inhibitory indices > 90.0% at 1.0 mg/mL against F. oxysporum f sp. cucumerium and B. cinerea. Furthermore, the chitosan derivatives showed stronger antioxidant activity than chitosan, especially 2.3HBPATC and 2.3.4HBPATC with inhibitory indices of 100.0% at 1.6 mg/mL against DPPH and superoxide radicals. Based on these data, it is reasonable to suggest that the introduction of phenolic hydroxyl and halogen groups enhances the antifungal and antioxidant activity of chitosan. |
| WOS关键词 | N-SUBSTITUTED CHITOSAN ; ACTIVITY IN-VITRO ; INULIN DERIVATIVES ; ANTIBACTERIAL ; NANOPARTICLE |
| WOS研究方向 | Chemistry, Applied ; Chemistry, Organic ; Polymer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000488245300007 |
| 资助机构 | National Natural Science Foundation of ChinaNational Natural Science Foundation of China [41576156] ; seed project of Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences [YIC Y755031011] ; Natural Science Foundation of Shandong Province of ChinaNatural Science Foundation of Shandong Province [ZR2017BD015] ; Science and Technology Service Network Initiative of Chinese Academy of sciences [KFJ-STSZDTP-023] |
| 源URL | [http://ir.yic.ac.cn/handle/133337/24789]  |
| 专题 | 海岸带生物资源高效利用研究与发展中心 烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室 |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Wei, LJ,Tan, WQ,Wang, G,et al. The antioxidant and antifungal activity of chitosan derivatives bearing Schiff bases and quaternary ammonium salts[J]. CARBOHYDRATE POLYMERS,2019,226:UNSP 115256. |
| APA | Wei, LJ,Tan, WQ,Wang, G,Li, Q,Dong, F,&Guo, ZY.(2019).The antioxidant and antifungal activity of chitosan derivatives bearing Schiff bases and quaternary ammonium salts.CARBOHYDRATE POLYMERS,226,UNSP 115256. |
| MLA | Wei, LJ,et al."The antioxidant and antifungal activity of chitosan derivatives bearing Schiff bases and quaternary ammonium salts".CARBOHYDRATE POLYMERS 226(2019):UNSP 115256. |
入库方式： OAI收割
来源：烟台海岸带研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。