Synthesis, Characterization, and Antifungal Activity of Schiff Bases of Inulin Bearing Pyridine ring
文献类型：期刊论文
| 作者 | Wei, LJ; Tan, WQ ; Zhang, JJ; Mi, YQ; Dong, F; Li, Q; Guo, ZY
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| 刊名 | POLYMERS
 |
| 出版日期 | 2019-02 |
| 卷号 | 11期号:2页码:371 |
| 关键词 | inulin Schiff base antifungal |
| DOI | 10.3390/polym11020371 |
| 产权排序 | [Wei, Lijie ; Tan, Wenqiang ; Zhang, Jingjing ; Mi, Yingqi ; Dong, Fang ; Li, Qing ; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China ; [Wei, Lijie ; Zhang, Jingjing ; Mi, Yingqi ; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 文献子类 | Article |
| 英文摘要 | As a renewable, biocompatible, and biodegradable polysaccharide, inulin has a good solubility in water and some physiological functions. Chemical modification is one of the important methods to improve the bioactivity of inulin. In this paper, based on 6-amino-6-deoxy-3,4-acetyl inulin (3), three kinds of Schiff bases of inulin bearing pyridine rings were successfully designed and synthesized. Detailed structural characterization was carried out using FTIR, C-13 NMR, and H-1 NMR spectroscopy, and elemental analysis. Moreover, the antifungal activity of Schiff bases of inulin against three plant pathogenic fungi, including Botrytis cinerea, Fusarium oxysporum f.sp.niveum, and Phomopsis asparagi, were evaluated using in vitro hypha measurements. Inulin, as a natural polysaccharide, did not possess any antifungal activity at the tested concentration against the targeted fungi. Compared with inulin and the intermediate product 6-amino-6-deoxy-3,4-acetyl inulin (3), all the synthesized Schiff bases of inulin derivatives with >54.0% inhibitory index at 2.0 mg/mL exhibited enhanced antifungal activity. 3NS, with an inhibitory index of 77.0% exhibited good antifungal activity against Botrytis cinerea at 2.0 mg/mL. The synthesized Schiff bases of inulin bearing pyridine rings can be prepared for novel antifungal agents to expand the application of inulin. |
| WOS关键词 | CHITOSAN DERIVATIVES ; ANTIOXIDANT ACTIVITY ; ANTIBACTERIAL |
| WOS研究方向 | Polymer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000460296000185 |
| 资助机构 | National Natural Science Foundation of ChinaNational Natural Science Foundation of China [41576156] ; seed project of Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences [YIC Y755031011] ; Natural Science Foundation of Shandong Province of ChinaNatural Science Foundation of Shandong Province [ZR 2017BD015] ; Science and Technology Service Network Initiative of Chinese Academy of sciences [KFJ-STSZDTP-023] |
| 源URL | [http://ir.yic.ac.cn/handle/133337/25004]  |
| 专题 | 海岸带生物资源高效利用研究与发展中心 烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室 烟台海岸带研究所_污染过程与控制实验室 |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Wei, LJ,Tan, WQ,Zhang, JJ,et al. Synthesis, Characterization, and Antifungal Activity of Schiff Bases of Inulin Bearing Pyridine ring[J]. POLYMERS,2019,11(2):371. |
| APA | Wei, LJ.,Tan, WQ.,Zhang, JJ.,Mi, YQ.,Dong, F.,...&Guo, ZY.(2019).Synthesis, Characterization, and Antifungal Activity of Schiff Bases of Inulin Bearing Pyridine ring.POLYMERS,11(2),371. |
| MLA | Wei, LJ,et al."Synthesis, Characterization, and Antifungal Activity of Schiff Bases of Inulin Bearing Pyridine ring".POLYMERS 11.2(2019):371. |
入库方式： OAI收割
来源：烟台海岸带研究所
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