Smoking cues impair monitoring but not stopping during response inhibition in abstinent male smokers
文献类型:期刊论文
作者 | Zhao, Haichao4,5; Turel, Ofir1,3,8; Brevers, Damien7; Bechara, Antoine1,3; He, Qinghua2,5,6,9 |
刊名 | BEHAVIOURAL BRAIN RESEARCH |
出版日期 | 2020-05-27 |
卷号 | 386页码:9 |
ISSN号 | 0166-4328 |
关键词 | Smoking cue Response inhibition ACC pre-SM Abstinent smoker |
DOI | 10.1016/j.bbr.2020.112605 |
文献子类 | article |
英文摘要 | The attenuated inhibitory control of smokers is a stumbling block for treating nicotine dependence. Unfortunately, smokers are often exposed to cigarette-related salient cues, which may violate homeostasis, override self-control, and lead to relapse. To understand the mechanisms underlying these associations, we investigate the cognitive and neural processes of inhibitory control (including proactive and reactive inhibition) of smoking cues in abstinent smokers. Twenty-six smokers completed cue-reactivity and stop signal tasks during functional magnetic resonance imaging scans, on two separate sessions, 2-3 weeks apart one involved a neutral cue reactivity task, and the other a smoking cue reactivity task. Findings pointed to no significant subjective craving changes, or behavioral influences of smoking cues on proactive and reactive inhibition. However, abstinent smokers exhibited hyperactive brain reactivity in response to smoking versus neutral stimuli, in regions including the insula, amygdala, anterior cingulate cortex (ACC), and putamen. They also had hypoactive bilateral rostral ACC (rACC) and hyperactive right pre-supplementary motor area during reactive inhibition in smoking versus neutral conditions. Support vector regression analysis showed that activation of these regions predicted and correlated with reactive inhibition index (i.e., SSRT), alluding to the possibility of their involvement in the reactive inhibition. Subjective craving scores were predicted by and correlated with activation of bilateral dorsal and rostral ACC, supporting the ideas of their possible involvement in subjective craving. These findings suggest that smoking cues evoke hyperactive brain reactivity; this may interfere with normal performance monitoring and rapid reactive inhibition. These findings have important implication for treating smoking dependence. |
WOS关键词 | ANTERIOR CINGULATE CORTEX ; ATTENTIONAL BIAS ; FRONTAL-CORTEX ; IMPULSIVE BEHAVIOR ; PREFRONTAL CORTEX ; ALCOHOL CUES ; SELF-REPORT ; TIME-COURSE ; MOTOR AREA ; SIGNAL |
资助项目 | National Natural Science Foundation of China[31972906] ; Entrepreneurship and Innovation Program for Chongqing Overseas Returned Scholars[cx2017049] ; Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences[KLMH2019K05] ; High-end Foreign Expert Introduction Program[G20190022029] |
WOS研究方向 | Behavioral Sciences ; Neurosciences & Neurology |
语种 | 英语 |
出版者 | ELSEVIER |
WOS记录号 | WOS:000526072600015 |
资助机构 | National Natural Science Foundation of China ; Entrepreneurship and Innovation Program for Chongqing Overseas Returned Scholars ; Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences ; High-end Foreign Expert Introduction Program |
源URL | [http://ir.psych.ac.cn/handle/311026/31565] |
专题 | 心理研究所_中国科学院心理健康重点实验室 |
通讯作者 | He, Qinghua |
作者单位 | 1.Univ Southern Calif, Brain & Creat Inst, Los Angeles, CA 90007 USA 2.Beijing Normal Univ, Southwest Univ Branch, Collaborat Innovat Ctr Assessment Basic Educ Qual, Chongqing, Peoples R China 3.Univ Southern Calif, Dept Psychol, Los Angeles, CA 90007 USA 4.Beihang Univ, Sch Biol Sci & Med Engn, Beijing, Peoples R China 5.Southwest Univ, Fac Psychol, 2 Tiansheng Rd, Chongqing 400715, Peoples R China 6.Chongqing Collaborat Innovat Ctr Brain Sci, Chongqing, Peoples R China 7.Univ Luxembourg, Addict & Compuls Behav Lab ACB Lab, Dept Behav & Cognit Sci, Campus Belval, Esch Sur Alzette, Luxembourg 8.Calif State Univ Fullerton, Dept Informat Syst & Decis Sci, Fullerton, CA 92634 USA 9.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing, Peoples R China |
推荐引用方式 GB/T 7714 | Zhao, Haichao,Turel, Ofir,Brevers, Damien,et al. Smoking cues impair monitoring but not stopping during response inhibition in abstinent male smokers[J]. BEHAVIOURAL BRAIN RESEARCH,2020,386:9. |
APA | Zhao, Haichao,Turel, Ofir,Brevers, Damien,Bechara, Antoine,&He, Qinghua.(2020).Smoking cues impair monitoring but not stopping during response inhibition in abstinent male smokers.BEHAVIOURAL BRAIN RESEARCH,386,9. |
MLA | Zhao, Haichao,et al."Smoking cues impair monitoring but not stopping during response inhibition in abstinent male smokers".BEHAVIOURAL BRAIN RESEARCH 386(2020):9. |
入库方式: OAI收割
来源:心理研究所
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