CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research
文献类型：期刊论文
| 作者 | Xu, Qiang40,41; Guo, Lining40,41; Cheng, Jingliang39; Wang, Meiyun36,37,38; Geng, Zuojun35; Zhu, Wenzhen34; Zhang, Bing33; Liao, Weihua1,32; Qiu, Shijun30; Zhang, Hui29 |
| 刊名 | MOLECULAR PSYCHIATRY
 |
| 出版日期 | 2020-03-01 |
| 卷号 | 25期号:3页码:517-529 |
| ISSN号 | 1359-4184 |
| DOI | 10.1038/s41380-019-0627-6 |
| 通讯作者 | Yu, Chunshui(chunshuiyu@tmu.edu.cn) |
| 英文摘要 | The Chinese Imaging Genetics (CHIMGEN) study establishes the largest Chinese neuroimaging genetics cohort and aims to identify genetic and environmental factors and their interactions that are associated with neuroimaging and behavioral phenotypes. This study prospectively collected genomic, neuroimaging, environmental, and behavioral data from more than 7000 healthy Chinese Han participants aged 18-30 years. As a pioneer of large-sample neuroimaging genetics cohorts of non-Caucasian populations, this cohort can provide new insights into ethnic differences in genetic-neuroimaging associations by being compared with Caucasian cohorts. In addition to micro-environmental measurements, this study also collects hundreds of quantitative macro-environmental measurements from remote sensing and national survey databases based on the locations of each participant from birth to present, which will facilitate discoveries of new environmental factors associated with neuroimaging phenotypes. With lifespan environmental measurements, this study can also provide insights on the macro-environmental exposures that affect the human brain as well as their timing and mechanisms of action. |
| WOS关键词 | GENOME-WIDE ASSOCIATION ; ENVIRONMENT INTERACTION ; RISK PREDICTION ; WORKING-MEMORY ; PERSPECTIVE ; PHENOTYPES ; CHILDHOOD ; IMPACTS ; SCHIZOPHRENIA ; HERITABILITY |
| WOS研究方向 | Biochemistry & Molecular Biology ; Neurosciences & Neurology ; Psychiatry |
| 语种 | 英语 |
| 出版者 | NATURE PUBLISHING GROUP |
| WOS记录号 | WOS:000516569700006 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/31398]  |
| 专题 | 心理研究所_中国科学院行为科学重点实验室 |
| 通讯作者 | Yu, Chunshui |
| 作者单位 | 1.Natl Clin Res Ctr Geriatr Disorder, Changsha 410008, Peoples R China 2.Xuzhou Med Univ, Affiliated Hosp, Dept Radiol, Xuzhou 221006, Jiangsu, Peoples R China 3.Univ Sci & Technol China, Sch Life Sci, Hefei 230026, Peoples R China 4.Univ Sci & Technol China, CAS Key Lab Brain Funct & Dis, Hefei 230026, Peoples R China 5.Wenzhou Med Univ, Yuying Childrens Hosp, Wenzhou 325000, Peoples R China 6.Wenzhou Med Univ, Dept Radiol, Affiliated Hosp 2, Wenzhou 325000, Peoples R China 7.Sichuan Univ, Ctr Med Imaging, Dept Radiol, West China Hosp, Chengdu 610041, Peoples R China 8.Logist Univ Chinese Peoples Armed Police Forces, Pingjin Hosp, Dept Radiol, Tianjin 300162, Peoples R China 9.Dalian Med Univ, Dept Radiol, Affiliated Hosp 1, Dalian 116011, Peoples R China 10.Tianjin First Ctr Hosp, Dept Radiol, Tianjin 300192, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Qiang,Guo, Lining,Cheng, Jingliang,et al. CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research[J]. MOLECULAR PSYCHIATRY,2020,25(3):517-529. |
| APA | Xu, Qiang.,Guo, Lining.,Cheng, Jingliang.,Wang, Meiyun.,Geng, Zuojun.,...&Yu, Chunshui.(2020).CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research.MOLECULAR PSYCHIATRY,25(3),517-529. |
| MLA | Xu, Qiang,et al."CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research".MOLECULAR PSYCHIATRY 25.3(2020):517-529. |
入库方式： OAI收割
来源：心理研究所
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