Phlegmadines B and C, two Lycopodium alkaloids with 6/5/5/5/7 pentacyclic skeleton from Phlegmariurus phlegmaria
文献类型：期刊论文
| 作者 | Zhang, Zhi-Jun; Zhu, Qin-Feng; Wu, Xing-De; Zhao, Qin-Shi
|
| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2020-01-09 |
| 卷号 | 61期号:2页码:4 |
| 关键词 | Lycopodium alkaloids Phlegmariurus phlegmaria Phlegmadines Neurotrophic effects |
| ISSN号 | 0040-4039 |
| DOI | 10.1016/j.tetlet.2019.151381 |
| 通讯作者 | Zhao, Qin-Shi(qinshizhao@mail.kib.ac.cn) |
| 英文摘要 | Two Lycopodium alkaloids named phlegmadines B (1) and C (2), along with biogenetically related known compounds 3-6, were obtained from Phlegmariurus phlegmaria. Their structures were elucidated based on NMR spectroscopic analysis, and the absolute configuration of I was determined by single-crystal X-ray diffraction. Compounds 1 and 2 represent the first pentacyclic (6/5/5/5/7) C16N2 Lycopodium alkaloid skeleton. In addition, a possible biosynthetic pathway for 1 and 2 was proposed. Moreover, compound 1 exhibited moderate neurotrophic effects on PC12 cells. (C) 2019 Elsevier Ltd. All rights reserved. |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000509777000005 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/70536]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Zhao, Qin-Shi |
| 作者单位 | Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Zhi-Jun,Zhu, Qin-Feng,Wu, Xing-De,et al. Phlegmadines B and C, two Lycopodium alkaloids with 6/5/5/5/7 pentacyclic skeleton from Phlegmariurus phlegmaria[J]. TETRAHEDRON LETTERS,2020,61(2):4. |
| APA | Zhang, Zhi-Jun,Zhu, Qin-Feng,Wu, Xing-De,&Zhao, Qin-Shi.(2020).Phlegmadines B and C, two Lycopodium alkaloids with 6/5/5/5/7 pentacyclic skeleton from Phlegmariurus phlegmaria.TETRAHEDRON LETTERS,61(2),4. |
| MLA | Zhang, Zhi-Jun,et al."Phlegmadines B and C, two Lycopodium alkaloids with 6/5/5/5/7 pentacyclic skeleton from Phlegmariurus phlegmaria".TETRAHEDRON LETTERS 61.2(2020):4. |
入库方式： OAI收割
来源：昆明植物研究所
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