A Novel bis-indole Alkaloid from the Flowers of Rauvolfia yunnanensis Tsiang and its Antihypertension Activity
文献类型：期刊论文
| 作者 | Wang, Haibo1,2,3; Liu, Xikui3 |
| 刊名 | LETTERS IN ORGANIC CHEMISTRY
 |
| 出版日期 | 2020 |
| 卷号 | 17期号:2页码:96-100 |
| 关键词 | Alkaloid Bis-indole alkaloid Rauvolfia yunnanensis rauvolfia flowers antihypertension reserpine |
| ISSN号 | 1570-1786 |
| DOI | 10.2174/1570178616666190126153703 |
| 通讯作者 | Wang, Haibo(wanghb616@163.com) |
| 英文摘要 | A novel bis-indole alkaloid was isolated from the flowers of Rauvolfia Yunnanensis Tsiang. Its structure was elucidated as 10,11'- dimethoxy-11,10'-bis-[N(a)-methyl deacetyldeformyl- 1,2-dihydro alcuammiline(2 beta)] (1) on the basis of spectroscopic analysis, including 1D and 2D NMR techniques as well as IIRESI-MS and comparison with data from the literature. The bis-indole alkaloid displayed more potent antihypertension activity and much lower hepatotoxicity in vivo than Reserpine. |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000506001100003 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/70570]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Wang, Haibo |
| 作者单位 | 1.Zhejiang Hongyuan Pharmaceut Co Ltd, Linhai 317016, Zhejiang, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Haibo,Liu, Xikui. A Novel bis-indole Alkaloid from the Flowers of Rauvolfia yunnanensis Tsiang and its Antihypertension Activity[J]. LETTERS IN ORGANIC CHEMISTRY,2020,17(2):96-100. |
| APA | Wang, Haibo,&Liu, Xikui.(2020).A Novel bis-indole Alkaloid from the Flowers of Rauvolfia yunnanensis Tsiang and its Antihypertension Activity.LETTERS IN ORGANIC CHEMISTRY,17(2),96-100. |
| MLA | Wang, Haibo,et al."A Novel bis-indole Alkaloid from the Flowers of Rauvolfia yunnanensis Tsiang and its Antihypertension Activity".LETTERS IN ORGANIC CHEMISTRY 17.2(2020):96-100. |
入库方式： OAI收割
来源：昆明植物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。