Elastic theories of single DNA molecules
文献类型：会议论文
| 作者 | Zhou, H; Zhang, Y; Ou-Yang, ZC
|
| 出版日期 | 2002 |
| 会议日期 | JUL 15-21, 2001 |
| 会议地点 | CANCUN, MEXICO |
| 关键词 | DOUBLE-STRANDED DNA SUPERCOILED DNA DOUBLE-HELIX POLYMERASE MECHANICS |
| 卷号 | 306 |
| 期号 | 1-4 |
| DOI | 10.1016/S0378-4371(02)00513-7 |
| 页码 | 359-367 |
| 英文摘要 | We study the elastic responses of double- (ds) and single-stranded (ss) DNA at external force fields. A double-strand-polymer elastic model is constructed and solved by path integral methods and Monte Carlo simulations to understand dsDNA entropic elasticity, cooperative extensibility, and supercoiling property. The good agreement with experiments indicates that short-ranged base-pair stacking interaction is crucial for the stability and the high deformability of dsDNA. Hairpin-coil transition in ssDNA is studied with generating function method. A threshold force is needed to pull the ssDNA hairpin patterns, stabilised by base pairing and base-pair stacking, into random coils. This phase transition is predicted to be of first order for stacking potential higher than some critical level, in accordance with observations. (C) 2002 Elsevier Science B.V. All rights reserved. |
| 会议录 | PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS
 |
| 会议录出版者 | ELSEVIER SCIENCE BV |
| 会议录出版地 | AMSTERDAM |
| 语种 | 英语 |
| URL标识 | 查看原文 |
| ISSN号 | 0378-4371 |
| WOS研究方向 | Physics |
| 源URL | [http://ir.itp.ac.cn/handle/311006/23746]  |
| 专题 | SCI会议论文 |
| 作者单位 | 1.Chinese Acad Sci, Inst Theoret Phys, Beijing 100080, Peoples R China 2.Max Planck Inst Colloids & Interfaces, D-14476 Golm, Germany 3.Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, H,Zhang, Y,Ou-Yang, ZC. Elastic theories of single DNA molecules[C]. 见:. CANCUN, MEXICO. JUL 15-21, 2001. |
入库方式： OAI收割
来源：理论物理研究所
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