Chemical Composition and the Cytotoxic, Antimicrobial, and Anti-Inflammatory Activities of the Fruit Peel Essential Oil from Spondias pinnata (Anacardiaceae) in Xishuangbanna, Southwest China
文献类型:期刊论文
作者 | Li, Ren; Yang, Jing-Jing; Song, Xing-Zhen; Wang, Yuan-Fei; Corlett, Richard T.; Xu, You-Kai; Hu, Hua-Bin |
刊名 | MOLECULES |
出版日期 | 2020 |
卷号 | 25期号:x页码:- |
ISSN号 | 1420-3049 |
关键词 | Spondias pinnata essential oil antimicrobial anti-inflammatory Aspergillus fumigatus Xishuangbanna |
DOI | 10.3390/molecules25020343 |
英文摘要 | Spondias pinnata (Linn. f.) Kurz (Anacardiaceae) is widely distributed in tropical Asia, where it is commonly used as a vegetable and fruit, and is attracting increasing research attention. In this study, we investigated the chemical composition and the cytotoxic, antimicrobial, and anti-inflammatory activities of the fruit peel essential oil of S. pinnata (EOSP), which has been consumed as a medicine and condiment in Xishuangbanna, southwest China. A total of 40 components were identified by Gas Chromatography/Mass spectrometry (GC-MS), representing 95.19% of the EOSP, with furfural (17.14%), alpha-terpineol (13.09%), and ethyl benzoate (9.05%) as the main constituents. EOSP has moderate cytotoxic activity against five cancer cells and obvious antimicrobial activity against five pathogenic strains. In particular, EOSP (Minimal Inhibitory and Fungicidal Concentration, MIC and MFC, 1632 mu g/mL) showed a 32-times higher inhibition effect against Aspergillus fumigatus than the positive control Tigecycline (MIC and MBC 5121024 mu g/mL). EOSP also showed strong anti-inflammatory activity by significantly inhibiting nitric oxide (NO) production induced by lipopolysaccharide (LPS) in RAW 264.7 cell lines at 0.08 parts per thousand, with no effect on cell viability. These bioactivities of S. pinnata fruit peel validate its traditional uses and suggest that it could be a new source of natural antimicrobial and anti-inflammatory agents for food or medical industries. |
学科主题 | Biochemistry & Molecular Biology ; Chemistry |
语种 | 英语 |
WOS记录号 | WOS:000515381800105 |
源URL | [http://ir.xtbg.org.cn/handle/353005/11700] |
专题 | 西双版纳热带植物园_民族植物学研究组 |
作者单位 | 1.[Li, Ren 2.Corlett, Richard T.] Chinese Acad Sci, Southeast Asia Biodivers Res Inst, Mengla 666303, Yunnan, Peoples R China 3.Corlett, Richard T.] Chinese Acad Sci, Ctr Integrat Conservat, Xishuangbanna Trop Bot Garden, Mengla 666303, Yunnan, Peoples R China 4.Chinese Acad Sci, Beijing 100049, Peoples R China 5.Beijing Inst Pharmacol & Toxicol, Natl Engn Res Ctr Emergency Drug, Beijing 100850, Peoples R China 6.Chinese Acad Sci, CAS Key Lab Trop Plant Resources & Sustainable Us, Xishuangbanna Trop Bot Garden, Mengla 666303, Yunnan, Peoples R China 7.[Wang, Yuan-Fei 8.Xu, You-Kai 9.Yunnan Univ Tradit Chinese Med, Kunming 650500, Yunnan, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Ren,Yang, Jing-Jing,Song, Xing-Zhen,et al. Chemical Composition and the Cytotoxic, Antimicrobial, and Anti-Inflammatory Activities of the Fruit Peel Essential Oil from Spondias pinnata (Anacardiaceae) in Xishuangbanna, Southwest China[J]. MOLECULES,2020,25(x):-. |
APA | Li, Ren.,Yang, Jing-Jing.,Song, Xing-Zhen.,Wang, Yuan-Fei.,Corlett, Richard T..,...&Hu, Hua-Bin.(2020).Chemical Composition and the Cytotoxic, Antimicrobial, and Anti-Inflammatory Activities of the Fruit Peel Essential Oil from Spondias pinnata (Anacardiaceae) in Xishuangbanna, Southwest China.MOLECULES,25(x),-. |
MLA | Li, Ren,et al."Chemical Composition and the Cytotoxic, Antimicrobial, and Anti-Inflammatory Activities of the Fruit Peel Essential Oil from Spondias pinnata (Anacardiaceae) in Xishuangbanna, Southwest China".MOLECULES 25.x(2020):-. |
入库方式: OAI收割
来源:西双版纳热带植物园
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