中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Quality assessment of herbal medicines based on chemical fingerprints combined with chemometrics approach: A review

文献类型:期刊论文

作者Li, Yun1,2; Shen, Yao2,3; Yao, Chang-liang2,3; Guo, De-an1,2,3
刊名JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
出版日期2020-06-05
卷号185页码:18
ISSN号0731-7085
关键词Herbal medicine Chemical fingerprints Analytical techniques Chemometrics Quality assessment
DOI10.1016/j.jpba.2020.113215
通讯作者Guo, De-an(daguo@simm.ac.cn)
英文摘要Herbal medicine (HM) has been playing a pivotal role in maintaining human health since ancient times, and its therapeutic theory and clinical experience are the precious traditional medical knowledge reserves. As HM occupies an important position in its own right in global healthcare systems, robust quality assessment and control over its complex chemical composition was of great significance to assure its efficacy and safety. Over the past decades, the concept of HM chemical fingerprints aiming to obtain a comprehensive characterization of complex chemical matrices has become one of the most convincing tools for the quality assessment of HM. This review summarizes the recent analytical techniques used to generate HM chemical fingerprints, including chromatography, vibrational spectroscopy, nuclear magnetic resonance spectroscopy, and mass spectrometry. The advantages, drawbacks, and the application scope of each technology have been scrutinized in an attempt to better understand the data analysis. Furthermore, HM fingerprints together with multivariate and multiway chemometrics methods used for different application domains, such as similarity, exploratory, classification, and regression analysis, have also been discussed and illustrated with a few typical studies. The article provides a general picture and workflow of fingerprinting analyses that have been used for the quality assessment of HM. (C) 2020 Elsevier B.V. All rights reserved.
WOS关键词NEAR-INFRARED SPECTROSCOPY ; TIME MASS-SPECTROMETRY ; PRINCIPAL COMPONENT ANALYSIS ; DIODE-ARRAY DETECTOR ; X-RAY-FLUORESCENCE ; COMPREHENSIVE 2-DIMENSIONAL SEPARATIONS ; INDUCED BREAKDOWN SPECTROSCOPY ; MULTIVARIATE DATA-ANALYSIS ; DATA FUSION STRATEGY ; GEOGRAPHICAL ORIGIN
资助项目National Natural Science Foundation[81530095] ; National Key R&D Program of China[2018YFC1707900]
WOS研究方向Chemistry ; Pharmacology & Pharmacy
语种英语
出版者ELSEVIER
WOS记录号WOS:000532677100008
源URL[http://119.78.100.183/handle/2S10ELR8/280015]  
专题中国科学院上海药物研究所
通讯作者Guo, De-an
作者单位1.China Pharmaceut Univ, Sch Tradit Chinese Pharm, Tongjiaxiang 24, Nanjing 210009, Peoples R China
2.Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai Inst Mat Med, Natl Engn Lab TCM Standardizat Technol, Haike Rd 501, Shanghai 201203, Peoples R China
3.GenChim Testing Technol Shanghai Co Ltd, Meiyue Rd 81, Shanghai 200131, Peoples R China
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GB/T 7714
Li, Yun,Shen, Yao,Yao, Chang-liang,et al. Quality assessment of herbal medicines based on chemical fingerprints combined with chemometrics approach: A review[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,2020,185:18.
APA Li, Yun,Shen, Yao,Yao, Chang-liang,&Guo, De-an.(2020).Quality assessment of herbal medicines based on chemical fingerprints combined with chemometrics approach: A review.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,185,18.
MLA Li, Yun,et al."Quality assessment of herbal medicines based on chemical fingerprints combined with chemometrics approach: A review".JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 185(2020):18.

入库方式: OAI收割

来源:上海药物研究所

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