Daphnillonins A and B: Alkaloids Representing Two Unknown Carbon Skeletons from Daphniphyllum longeracemosum
文献类型：期刊论文
| 作者 | Zhang, Dong-Dong1,2; Xu, Jin-Biao1,2; Fan, Yao-Yue1,2; Gan, Li-She3; Zhang, Hua1,2; Yue, Jian-Min1,2
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| 刊名 | JOURNAL OF ORGANIC CHEMISTRY
 |
| 出版日期 | 2020-03-06 |
| 卷号 | 85期号:5页码:3742-3747 |
| ISSN号 | 0022-3263 |
| DOI | 10.1021/acs.joc.9b03310 |
| 通讯作者 | Yue, Jian-Min(jmyue@simm.ac.cn) |
| 英文摘要 | Two highly rearranged daphniphyllum alkaloids, daphnillonins A (1) and B (2), were isolated from Daphniphyllum longeracemosum and structurally characterized by a combination of diverse methods, including the calculation of electronic circular dichroism. Compound 1 possesses an unprecedented carbon architecture with a very unique 8-methyl-6-azabicyclo[3.2.1]octane moiety, and compound 2 represents a new carbon skeleton with an uncommon 7/6/5/7/5/5-fused ring system. The biosynthetic pathways for the two alkaloids were proposed with the concurrent major alkaloids as the precursors. |
| WOS关键词 | CHEMISTRY |
| 资助项目 | National Natural Science Foundation[21532007] ; Drug Innovation Major Project[2018ZX09711001-001-005] ; [CASIMM0120181001] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000518875700079 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/280875]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Yue, Jian-Min |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 3.Zhejiang Univ, Coll Pharmaceut Sci, Hangzhou 310058, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Dong-Dong,Xu, Jin-Biao,Fan, Yao-Yue,et al. Daphnillonins A and B: Alkaloids Representing Two Unknown Carbon Skeletons from Daphniphyllum longeracemosum[J]. JOURNAL OF ORGANIC CHEMISTRY,2020,85(5):3742-3747. |
| APA | Zhang, Dong-Dong,Xu, Jin-Biao,Fan, Yao-Yue,Gan, Li-She,Zhang, Hua,&Yue, Jian-Min.(2020).Daphnillonins A and B: Alkaloids Representing Two Unknown Carbon Skeletons from Daphniphyllum longeracemosum.JOURNAL OF ORGANIC CHEMISTRY,85(5),3742-3747. |
| MLA | Zhang, Dong-Dong,et al."Daphnillonins A and B: Alkaloids Representing Two Unknown Carbon Skeletons from Daphniphyllum longeracemosum".JOURNAL OF ORGANIC CHEMISTRY 85.5(2020):3742-3747. |
入库方式： OAI收割
来源：上海药物研究所
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