Applications of Fourier transform infrared spectroscopy to pharmaceutical preparations
文献类型：期刊论文
| 作者 | Song, Yijie1,2; Cong, Yuanhua3; Wang, Bing2,3; Zhang, Ning1 |
| 刊名 | EXPERT OPINION ON DRUG DELIVERY
 |
| 出版日期 | 2020-04-02 |
| 卷号 | 17期号:4页码:551-571 |
| 关键词 | FTIR FTIR imaging nano-FTIR drug release drug delivery biological detection |
| ISSN号 | 1742-5247 |
| DOI | 10.1080/17425247.2020.1737671 |
| 通讯作者 | Wang, Bing(bwang@simm.ac.cn) ; Zhang, Ning(ningzh18@126.com) |
| 英文摘要 | Introduction: Various pharmaceutical preparations are widely used for clinical treatment. Elucidation of the mechanisms of drug release and evaluation of drug efficacy in biological samples are important in drug design and drug quality control. Areas covered: This review classifies recent applications of Fourier transform infrared (FTIR) spectroscopy in the field of medicine to comprehend drug release and diffusion. Drug release is affected by many factors of preparations, such as drug delivery system and microstructure polymorphism. The applications of FTIR imaging and nano-FTIR technique in biological samples lay a foundation for studying drug mechanism in vivo. Expert opinion: FTIR spectroscopy meets the research needs on preparations to understand the processes and mechanisms underlying drug release. The combination of attenuated total reflectance-FTIR imaging and nano-FTIR accompanied by chemometrics is a potent tool to overcome the deficiency of conventional infrared detection. FTIR shows an enormous potential in drug characterization, drug quality control, and bio-sample detection. |
| WOS关键词 | DRUG-DELIVERY SYSTEM ; IN-VITRO ; FT-IR ; PAPAVERINE HYDROCHLORIDE ; STRUCTURAL-CHANGES ; DISSOLUTION TESTS ; RELEASE PROPERTY ; MELT EXTRUSION ; LIVING CELLS ; NANO-CARRIER |
| 资助项目 | Program of Shanghai Committee of Science and Technology, China[17401902300] |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000519458800001 |
| 出版者 | TAYLOR & FRANCIS LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/281016]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Wang, Bing; Zhang, Ning |
| 作者单位 | 1.Shanghai Univ Tradit Chinese Med, Expt Ctr Sci & Technol, 1200 Cai Lun Rd, Shanghai 201203, Peoples R China 2.Shanghai Univ Tradit Chinese Med, Sch Pharm, Shanghai, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, Pharmaceut Res Ctr, 501 Hai Ke Rd, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Song, Yijie,Cong, Yuanhua,Wang, Bing,et al. Applications of Fourier transform infrared spectroscopy to pharmaceutical preparations[J]. EXPERT OPINION ON DRUG DELIVERY,2020,17(4):551-571. |
| APA | Song, Yijie,Cong, Yuanhua,Wang, Bing,&Zhang, Ning.(2020).Applications of Fourier transform infrared spectroscopy to pharmaceutical preparations.EXPERT OPINION ON DRUG DELIVERY,17(4),551-571. |
| MLA | Song, Yijie,et al."Applications of Fourier transform infrared spectroscopy to pharmaceutical preparations".EXPERT OPINION ON DRUG DELIVERY 17.4(2020):551-571. |
入库方式： OAI收割
来源：上海药物研究所
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