RNA Methylation m(6)A: A New Code and Drug Target?
文献类型：期刊论文
| 作者 | Lai, Gan-Qiang1,2; Zhou, Lin-Lin1,2; Yang, Cai-Guang1,2
|
| 刊名 | CHINESE JOURNAL OF CHEMISTRY
 |
| 出版日期 | 2020-04-01 |
| 卷号 | 38期号:4页码:420-421 |
| 关键词 | m(6)A Epitranscriptomics Small-molecule intervention Drug discovery RNA |
| ISSN号 | 1001-604X |
| DOI | 10.1002/cjoc.201900490 |
| 通讯作者 | Yang, Cai-Guang(yangcg@simm.ac.cn) |
| 英文摘要 | The m(6)A-RNA modification is a dynamic and reversible process, which has emerged as a new RNA code for the regulation of gene expression. The functional network of methyltransferases (writers), demethylases (erasers), and binding proteins (readers) modulate the level of m(6)A modification. Dysfunction of RNA methylation has been associated with various fundamental biological processes and human diseases. Herein, we briefly introduce an understanding-enabled manipulation on m(6)A-RNA modification with an emphasis on the use of small-molecule intervention. |
| WOS关键词 | DEMETHYLASE |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000520386700014 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/281188]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Yang, Cai-Guang |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lai, Gan-Qiang,Zhou, Lin-Lin,Yang, Cai-Guang. RNA Methylation m(6)A: A New Code and Drug Target?[J]. CHINESE JOURNAL OF CHEMISTRY,2020,38(4):420-421. |
| APA | Lai, Gan-Qiang,Zhou, Lin-Lin,&Yang, Cai-Guang.(2020).RNA Methylation m(6)A: A New Code and Drug Target?.CHINESE JOURNAL OF CHEMISTRY,38(4),420-421. |
| MLA | Lai, Gan-Qiang,et al."RNA Methylation m(6)A: A New Code and Drug Target?".CHINESE JOURNAL OF CHEMISTRY 38.4(2020):420-421. |
入库方式： OAI收割
来源：上海药物研究所
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