中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 上海药物研究所
  3. 中国科学院上海药物研究所
  4. 新药研究国家重点实验室
A fluorogenic probe for tracking GSH flux in developing neurons

文献类型：期刊论文

作者Zong, Haichao1,2; Peng, Jiayi3; Li, Xiao-Rong3; Liu, Meng1,2; Hu, Yongzhou3; Li, Jia1,2; Zang, Yi1,2; Li, Xin3; James, Tony D.4
刊名CHEMICAL COMMUNICATIONS
出版日期2020-01-14
卷号56期号:4页码:515-518
ISSN号1359-7345
DOI10.1039/c9cc07753g
通讯作者Zang, Yi(yzang@simm.ac.cn) ; Li, Xin(lixin81@zju.edu.cn)
英文摘要Understanding GSH flux in developing neurons is prerequisite to reveal its role in neuronal development but necessiates an ultra-sensitive assay. By systematically exploring key structural factors determing probe sensitivity in live cells, we developed a fluorogenic probe capable of imaging subtle GSH fluctuations in developing neurons.
WOS关键词REVERSIBLE FLUORESCENT-PROBE ; SELECTIVE DETECTION ; GLUTATHIONE ; ESTABLISHMENT ; POLARITY ; CYSTEINE ; CELLS
资助项目National Natural Science Foundations of China[21778048] ; National Natural Science Foundations of China[81673489] ; National Natural Science Foundations of China[31871414] ; National Natural Science Foundations of China[81125023] ; Natural Science Foundation of Zhejiang Province, China[LR18H300001] ; Shanghai Science and Technology Development Funds[19YF1457500] ; National Science & Technology Major Project Key New Drug Creation and Manufacturing Program[2018ZX09711002-010-004] ; National Science & Technology Major Project Key New Drug Creation and Manufacturing Program[2018ZX09711002-007-002] ; Royal Society
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000506632200038
出版者ROYAL SOC CHEMISTRY
源URL[http://119.78.100.183/handle/2S10ELR8/281591]  
专题新药研究国家重点实验室
通讯作者Zang, Yi; Li, Xin
作者单位1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Zhejiang Univ, Coll Pharmaceut Sci, Hangzhou 310058, Zhejiang, Peoples R China
4.Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England
推荐引用方式
GB/T 7714		 Zong, Haichao,Peng, Jiayi,Li, Xiao-Rong,et al. A fluorogenic probe for tracking GSH flux in developing neurons[J]. CHEMICAL COMMUNICATIONS,2020,56(4):515-518.
APA Zong, Haichao.,Peng, Jiayi.,Li, Xiao-Rong.,Liu, Meng.,Hu, Yongzhou.,...&James, Tony D..(2020).A fluorogenic probe for tracking GSH flux in developing neurons.CHEMICAL COMMUNICATIONS,56(4),515-518.
MLA Zong, Haichao,et al."A fluorogenic probe for tracking GSH flux in developing neurons".CHEMICAL COMMUNICATIONS 56.4(2020):515-518.

入库方式： OAI收割

来源：上海药物研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。