Natural constituents from food sources: potential therapeutic agents against muscle wasting
文献类型：期刊论文
| 作者 | Shen, Shengnan2; Yu, Hua2; Gan, Lishe3; Ye, Yang1,4 ; Lin, Ligen2
|
| 刊名 | FOOD & FUNCTION
 |
| 出版日期 | 2019-11-01 |
| 卷号 | 10期号:11页码:6967-6986 |
| ISSN号 | 2042-6496 |
| DOI | 10.1039/c9fo00912d |
| 通讯作者 | Lin, Ligen(ligenl@um.edu.mo) |
| 英文摘要 | Skeletal muscle wasting is highly correlated with not only reduced quality of life but also higher morbidity and mortality. Although an increasing number of patients are suffering from various kinds of muscle atrophy and weakness, there is still no effective therapy available, and skeletal muscle is considered as an under-medicated organ. Food provided not only essential macronutrients but also functional substances involved in the modulation of the physiological systems of our body. Natural constituents from commonly consumed dietary plants, either extracts or compounds, have attracted more and more attention to be developed as agents for preventing and treating muscle wasting due to their safety and effectiveness, as well as structural diversity. This review provides an overview of the mechanistic aspects of muscle wasting, and summarizes the extracts and compounds from food sources as potential therapeutic agents against muscle wasting. |
| WOS关键词 | ACTIVATED PROTEIN-KINASE ; INDUCED SKELETAL-MUSCLE ; NECROSIS-FACTOR-ALPHA ; NF-KAPPA-B ; ENHANCES MYOGENIC DIFFERENTIATION ; FOXO TRANSCRIPTION FACTORS ; RNA EXPRESSION SIGNATURES ; CELL-CYCLE PROGRESSION ; UBIQUITIN LIGASES ; OXIDATIVE STRESS |
| 资助项目 | Science and Technology Development Fund, Macao SAR[FDCT 0031/2019/A1] ; National Natural Science Foundation of China[81872754] ; Research Fund of University of Macau[MYRG2017-00109-ICMS] ; Research Fund of University of Macau[MYRG2018-00037-ICMS] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Food Science & Technology |
| 语种 | 英语 |
| WOS记录号 | WOS:000497763600001 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/282035]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Lin, Ligen |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Nat Prod Chem Dept, Shanghai, Peoples R China 2.Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Macau, Peoples R China 3.Zhejiang Univ, Coll Pharmaceut Sci, Hangzhou, Zhejiang, Peoples R China 4.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Shen, Shengnan,Yu, Hua,Gan, Lishe,et al. Natural constituents from food sources: potential therapeutic agents against muscle wasting[J]. FOOD & FUNCTION,2019,10(11):6967-6986. |
| APA | Shen, Shengnan,Yu, Hua,Gan, Lishe,Ye, Yang,&Lin, Ligen.(2019).Natural constituents from food sources: potential therapeutic agents against muscle wasting.FOOD & FUNCTION,10(11),6967-6986. |
| MLA | Shen, Shengnan,et al."Natural constituents from food sources: potential therapeutic agents against muscle wasting".FOOD & FUNCTION 10.11(2019):6967-6986. |
入库方式： OAI收割
来源：上海药物研究所
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