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Recent progress in drug delivery

文献类型：期刊论文

作者Li, Chong2; Wang, Jiancheng3; Wang, Yiguang3; Gao, Huile4; Wei, Gang5; Huang, Yongzhuo1; Yu, Haijun1; Gan, Yong1; Wang, Yongjun6; Mei, Lin7
刊名ACTA PHARMACEUTICA SINICA B
出版日期2019-11-01
卷号9期号:6页码:1145-1162
关键词Pharmaceutics Drug delivery system Basic research Application Delivery strategy
ISSN号2211-3835
DOI10.1016/j.apsb.2019.08.003
通讯作者Wang, Jiancheng(wang-jc@bjmu.edu.cn)
英文摘要Drug delivery systems (DDS) are defined as methods by which drugs are delivered to desired tissues, organs, cells and subcellular organs for drug release and absorption through a variety of drug carriers. Its usual purpose to improve the pharmacological activities of therapeutic drugs and to overcome problems such as limited solubility, drug aggregation, low bioavailability, poor biodistribution, lack of selectivity, or to reduce the side effects of therapeutic drugs. During 2015-2018, significant progress in the research on drug delivery systems has been achieved along with advances in related fields, such as pharmaceutical sciences, material sciences and biomedical sciences. This review provides a concise overview of current progress in this research area through its focus on the delivery strategies, construction techniques and specific examples. It is a valuable reference for pharmaceutical scientists who want to learn more about the design of drug delivery systems. (C) 2019 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.
WOS关键词MESOPOROUS SILICA NANOPARTICLES ; IN-VIVO PHARMACOKINETICS ; ORAL DELIVERY ; SIRNA DELIVERY ; TARGETED NANOASSEMBLIES ; CANCER-IMMUNOTHERAPY ; COMBINATION THERAPY ; SENSITIVE VESICLES ; MEMBRANE-RECEPTORS ; TUMOR PENETRATION
资助项目National Natural Science Foundation of China[81773650] ; National Natural Science Foundation of China[81690264] ; National Natural Science Foundation of China[81673376] ; Drug Innovation Major Project of China[2018ZX09721003-004]
WOS研究方向Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000500912700004
出版者INST MATERIA MEDICA, CHINESE ACAD MEDICAL SCIENCES
源URL[http://119.78.100.183/handle/2S10ELR8/282117]  
专题中国科学院上海药物研究所
通讯作者Wang, Jiancheng
作者单位1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
2.Southwest Univ, Coll Pharmaceut Sci, Chongqing 400715, Peoples R China
3.Peking Univ, Sch Pharmaceut Sci, Beijing Key Lab Mol Pharmaceut & New Drug Deliver, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
4.Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Chengdu 610041, Sichuan, Peoples R China
5.Fudan Univ, Key Lab Smart Drug Delivery, Minist Educ, Shanghai 201203, Peoples R China
6.Shenyang Pharmaceut Univ, Sch Pharm, Shenyang 110016, Liaoning, Peoples R China
7.Sun Yat Sen Univ, Sch Pharmaceut Sci Shenzhen, Guangzhou 510275, Guangdong, Peoples R China
8.Soochow Univ, Sch Radiat Med & Protect, Suzhou 215123, Peoples R China
9.Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China
10.Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Pharm, Wuhan 430030, Hubei, Peoples R China
推荐引用方式
GB/T 7714		 Li, Chong,Wang, Jiancheng,Wang, Yiguang,et al. Recent progress in drug delivery[J]. ACTA PHARMACEUTICA SINICA B,2019,9(6):1145-1162.
APA Li, Chong.,Wang, Jiancheng.,Wang, Yiguang.,Gao, Huile.,Wei, Gang.,...&Jin, Yiguang.(2019).Recent progress in drug delivery.ACTA PHARMACEUTICA SINICA B,9(6),1145-1162.
MLA Li, Chong,et al."Recent progress in drug delivery".ACTA PHARMACEUTICA SINICA B 9.6(2019):1145-1162.

入库方式： OAI收割

来源：上海药物研究所

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