Hydrochromism behaviors of solid forms of chelerythrine hydrochloride
文献类型：期刊论文
| 作者 | Li, Meiqi1,3; Li, Zhen1,2; Wang, Jian-rong1 ; Mei, Xuefeng1,3
|
| 刊名 | CRYSTENGCOMM
 |
| 出版日期 | 2019-10-21 |
| 卷号 | 21期号:39页码:5915-5921 |
| ISSN号 | 1466-8033 |
| DOI | 10.1039/c9ce00933g |
| 通讯作者 | Mei, Xuefeng(xuefengmei@simm.ac.cn) |
| 英文摘要 | Chelerythrine hydrochloride (CHE-Cl), a salt of an unstable naturally fluorescent material, exhibited reversible hydrochromism fluorescence emissions. Three solid forms with high crystallinity were obtained via comprehensive crystallization investigations. Two of them presented green emission (G1: lambda(em) = 509.8 nm; G2, lambda(em) = 522.0 nm), and the other showed orange emission (O, lambda(em) = 558.8 nm) under 365 nm UV irradiation. Reversible water-triggered changes in the fluorescence color of CHE-Cl between G1/G2 and O were observed and fully characterized. Solid-state fluorescence spectroscopy (SFS), X-ray powder diffraction (XRPD) and single-crystal X-ray diffraction (SCXRD) experiments indicated that conformational changes and water-induced rearrangement of the crystal lattice under different stimuli were responsible for the reversible switching of the fluorescence between the solid forms of CHE-Cl. Density functional theory (DFT) calculations revealed that HOMO-LUMO energy band gaps were highly affected by the conformations and packing patterns of the CHE-Cl molecules. This result suggested an alternative approach involving salt formation to develop stimuli-response luminescent materials, especially for those with unstable chemical structures in the free base form. |
| WOS关键词 | ORGANIC-CRYSTALS ; PIEZOCHROMIC LUMINESCENCE ; EMISSION ; FLUORESCENCE ; PACKING ; COLOR |
| 资助项目 | Shanghai Natural Science Foundation[18ZR1447900] ; Youth Innovation Promotion Association CAS[2016257] ; CAS Key Technology Talent Program ; SANOFI-SIBS scholarship |
| WOS研究方向 | Chemistry ; Crystallography |
| 语种 | 英语 |
| WOS记录号 | WOS:000489243300006 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/282714]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Mei, Xuefeng |
| 作者单位 | 1.Chinese Acad Sci, Pharmaceut Analyt & Solid State Chem Res Ctr, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 2.Nanchang Univ, Coll Pharm, Nanchang 330006, Jiangxi, Peoples R China 3.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100099, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Meiqi,Li, Zhen,Wang, Jian-rong,et al. Hydrochromism behaviors of solid forms of chelerythrine hydrochloride[J]. CRYSTENGCOMM,2019,21(39):5915-5921. |
| APA | Li, Meiqi,Li, Zhen,Wang, Jian-rong,&Mei, Xuefeng.(2019).Hydrochromism behaviors of solid forms of chelerythrine hydrochloride.CRYSTENGCOMM,21(39),5915-5921. |
| MLA | Li, Meiqi,et al."Hydrochromism behaviors of solid forms of chelerythrine hydrochloride".CRYSTENGCOMM 21.39(2019):5915-5921. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。