advancesinthestudyofberberineanditsderivativesafocusonantiinflammatoryandantitumoreffectsinthedigestivesystem
文献类型：期刊论文
| 作者 | Zou Kun1; Li Zhao1; Zhang Yong2; Zhang Haoyue1; Li Bo2; Zhu Weiliang2 ; Shi Jiye3; Jia Qi1; Li Yiming1
|
| 刊名 | actapharmacologicasinica
 |
| 出版日期 | 2017 |
| 卷号 | 38期号:2页码:157 |
| 关键词 | berberine natural product anti-inflammatory drug anticancer drug digestive system structure-activity relationship |
| ISSN号 | 1671-4083 |
| DOI | 10.1038/aps.2016.125 |
| 英文摘要 | It has been widely recognized that inflammation, particularly chronic inflammation, can increase the risk of cancer and that the simultaneous treatment of inflammation and cancer may produce excellent therapeutic effects. Berberine, an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic with a long history. Over the past decade, many reports have demonstrated that this natural product and its derivatives have high activity against both cancer and inflammation. In this review, we summarize the advances in studing berberine and its derivatives as anti-inflammatory and anti-tumor agents in the digestive system; we also discuss their structure-activity relationship. These data should be useful for the development of this natural product as novel anticancer drugs with anti-inflammation activity. |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/282966]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.上海中医药大学 2.中国科学院上海药物研究所 3.UCB Biopharma SPRL, Chemin du Foriest |
| 推荐引用方式 GB/T 7714 | Zou Kun,Li Zhao,Zhang Yong,et al. advancesinthestudyofberberineanditsderivativesafocusonantiinflammatoryandantitumoreffectsinthedigestivesystem[J]. actapharmacologicasinica,2017,38(2):157. |
| APA | Zou Kun.,Li Zhao.,Zhang Yong.,Zhang Haoyue.,Li Bo.,...&Li Yiming.(2017).advancesinthestudyofberberineanditsderivativesafocusonantiinflammatoryandantitumoreffectsinthedigestivesystem.actapharmacologicasinica,38(2),157. |
| MLA | Zou Kun,et al."advancesinthestudyofberberineanditsderivativesafocusonantiinflammatoryandantitumoreffectsinthedigestivesystem".actapharmacologicasinica 38.2(2017):157. |
入库方式： OAI收割
来源：上海药物研究所
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