synthesischaracterizationandantitumoractivitiesofconicuzncomplexeswith14710tetrakis4nitrobenzyl14710tetraazacyclododecanemacrocyclicligand
文献类型：期刊论文
| 作者 | Huang Xiaoying1; Kong Deyuan2; Xie Yuli2; Xie Yuyuan2
|
| 刊名 | 结构化学
 |
| 出版日期 | 2000 |
| 卷号 | 19期号:1页码:39 |
| 关键词 | LANTHANIDE COMPLEXES MOLECULAR-STRUCTURE PHOSPHATE DIESTER EUROPIUM(III) LANTHANUM(III) ALCOHOL CRYSTAL RNA CONFORMATION CLEAVAGE synthesis macrocyclic ligand antitumor activity crystal structure |
| ISSN号 | 0254-5861 |
| 英文摘要 | New tetraazamacrocyclic ligand with 1, 4, 7, 10-tetrakis (4-nitrobenzyl) pendent groups (C36H40N8O8, M-r = 712. 76) crystallized in the monoclinic system, P2(1)/n space group with unit cell parameters: a = 7. 834(2), b = 22. 902(6) , c = 10. 147(3)Angstrom, beta = 106. 53(2)degrees, V = 1715(1) Angstrom (3), Z = 2, D-c= 1. 356 g/cm(3) (,) lambda(Mo-k alpha) = 0. 71069 Angstrom; mu = 0. 92cm(-1), F(000) = 752, T = 296K. The final R and R-w values are 0. 065 and 0. 066, respectively. The Cu( I ), Nit ( I ), Co( I ), Zn( I ) complexes with this new ligand have been synthesized and characterized by elemental analyses, IR, UV, ESI-MS and molar conductance, The macrocyclic ligand molecular structure is centrosymmetrical. All complexes are in accordance with the general formula: M(L)(NO3)(2) . nH(2)O (M = Co, Ni, Cu, n = 2; M = Zn, n = 4; L = C36H40-N8O8). The central metal ions coordinate to four nitrogen atoms of azamacrocycle and two oxygen atoms of one nitrate ion. Preliminary pharmacological tests against P-388 and A-549 tumor cell lines showed that all these complexes had considerable activities in vitro. |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/282988]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.Rugters University 2.中国科学院上海药物研究所 |
| 推荐引用方式 GB/T 7714 | Huang Xiaoying,Kong Deyuan,Xie Yuli,et al. synthesischaracterizationandantitumoractivitiesofconicuzncomplexeswith14710tetrakis4nitrobenzyl14710tetraazacyclododecanemacrocyclicligand[J]. 结构化学,2000,19(1):39. |
| APA | Huang Xiaoying,Kong Deyuan,Xie Yuli,&Xie Yuyuan.(2000).synthesischaracterizationandantitumoractivitiesofconicuzncomplexeswith14710tetrakis4nitrobenzyl14710tetraazacyclododecanemacrocyclicligand.结构化学,19(1),39. |
| MLA | Huang Xiaoying,et al."synthesischaracterizationandantitumoractivitiesofconicuzncomplexeswith14710tetrakis4nitrobenzyl14710tetraazacyclododecanemacrocyclicligand".结构化学 19.1(2000):39. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。