chromopeptideaahighlycytotoxicdepsipeptidefromthemarinesedimentderivedbacteriumchromobacteriumsphs1394
文献类型：期刊论文
| 作者 | Zhou Zhenfang2; Wang Xin2 ; Zhang Hui1; Sun Jingya2; Zheng Linghui1; Liu Hongchun2; Wang Jidong1; Shen Aijun2; Geng Meiyu2; Guo Yuewei2
|
| 刊名 | actapharmaceuticasinicab
 |
| 出版日期 | 2015 |
| 卷号 | 5期号:1页码:62 |
| 关键词 | Chromopeptide A Bacterium Depsipeptide Absolute configuration Marine-derived Sediments Cytotoxicity Chromobacterium sp |
| ISSN号 | 2211-3835 |
| 英文摘要 | A bicyclic depsipeptide, chromopeptide A (1),was isolated from a deep-sea-derived bacterium Chromobacterium sp. HS-13-94. Its structure was determined by extensive spectroscopic analysis and by comparison with a related known compound. The absolute configuration of chromopeptide A was established by X-ray diffraction analysis employing graphite monochromated Mo K_a radiation (λ=0.71073 A) with small Flack parameter 0.03. Chromopeptide A suppressed the proliferation of HL-60, K-562, and Ramos cells with average IC_(50) values of 7.7, 7.0, and 16.5 nmol/L, respectively. |
| 资助项目 | [National Marine '863' Project] ; [National Natural Science Foundation of China] |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/283409]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.Zhejiang Hisun Pharmaceutical Co., Ltd. 2.中国科学院上海药物研究所 |
| 推荐引用方式 GB/T 7714 | Zhou Zhenfang,Wang Xin,Zhang Hui,et al. chromopeptideaahighlycytotoxicdepsipeptidefromthemarinesedimentderivedbacteriumchromobacteriumsphs1394[J]. actapharmaceuticasinicab,2015,5(1):62. |
| APA | Zhou Zhenfang.,Wang Xin.,Zhang Hui.,Sun Jingya.,Zheng Linghui.,...&Guo Yuewei.(2015).chromopeptideaahighlycytotoxicdepsipeptidefromthemarinesedimentderivedbacteriumchromobacteriumsphs1394.actapharmaceuticasinicab,5(1),62. |
| MLA | Zhou Zhenfang,et al."chromopeptideaahighlycytotoxicdepsipeptidefromthemarinesedimentderivedbacteriumchromobacteriumsphs1394".actapharmaceuticasinicab 5.1(2015):62. |
入库方式： OAI收割
来源：上海药物研究所
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