Rapid Identification of Bibenzyls of Stemona sessilifolia using Hyphenated LC-UV-NMR and LC-MS Methods
文献类型：期刊论文
| 作者 | YANG Xinzhou; YANG Yiping ; KE Changqiang; KE Changqiang; YE Yang
|
| 刊名 | Chemical Research in Chinese Universities
 |
| 出版日期 | 2007 |
| 卷号 | 23期号:1页码:48 |
| 关键词 | Bibenzyls LC-UV-NMR |
| ISSN号 | 1005-9040 |
| 英文摘要 | As a part of the ongoing search for new constituents of Stemona species in China, chemical investigation of Stemona sessilifolia , a plant used in the traditional Chinese medicine to treat respiratory disorders, was carried out. To identify the chemical components rapidly, a selected sample of S. sessilifolia containing bibenzyls was tested using LC-ESIMS and analyzed further using stop-flow LC-UV-NMR, which was sensitive for the detection of the main constituents. LC microfractions were collected using the LC-UV-NMR technique and HR-EIMS off-line analysis was carried out on the collected fractions. This chemical screening strategy allowed for the on-line identification of the main constituents of S. sessilifolia and provided information that was useful for a further peak-guided isolation procedure. Using these methods, four bibenzyls were isolated: two known compounds, 3,5-dihydroxy-4-methyl bibenzyl( 1 ) and 3, 5-dihydroxy-2′-methoxy-4-methyl bibenzyl ( 2 ), and two novel compounds, 3, 3′-dihydroxy-5, 6′-dimethoxy bibenzyl ( 3 ) and 3,5-dihydroxy-2′,5′-dimethoxy bibenzyl ( 4 ). |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/283626]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 中国科学院上海药物研究所 |
| 推荐引用方式 GB/T 7714 | YANG Xinzhou,YANG Yiping,KE Changqiang,et al. Rapid Identification of Bibenzyls of Stemona sessilifolia using Hyphenated LC-UV-NMR and LC-MS Methods[J]. Chemical Research in Chinese Universities,2007,23(1):48. |
| APA | YANG Xinzhou,YANG Yiping,KE Changqiang,KE Changqiang,&YE Yang.(2007).Rapid Identification of Bibenzyls of Stemona sessilifolia using Hyphenated LC-UV-NMR and LC-MS Methods.Chemical Research in Chinese Universities,23(1),48. |
| MLA | YANG Xinzhou,et al."Rapid Identification of Bibenzyls of Stemona sessilifolia using Hyphenated LC-UV-NMR and LC-MS Methods".Chemical Research in Chinese Universities 23.1(2007):48. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。