preparationandapplicationoforderedmesoporoussilicananoparticlesinthetherapyanddiagnosisoftumor
文献类型：期刊论文
| 作者 | Ceng F(曾峰)1; Pan ZZ(潘真真)1; Zhang M(张梦)1; Huang YZ(黄永焯)1 ; Cui YN(崔彦娜)1; Xu Q(徐勤)2
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| 刊名 | progressinchemistry
 |
| 出版日期 | 2015 |
| 卷号 | 27期号:10页码:1356 |
| 关键词 | TARGETED DRUG-DELIVERY COLLOIDAL SUSPENSIONS MULTIDRUG-RESISTANCE ORGANIC TEMPLATES THIN-FILMS IN-VITRO CANCER SIZE DOXORUBICIN FACILE ordered mesoporous structure silica nanoparticles synthesis and modification tumor diagnosis and therapy |
| ISSN号 | 1005-281X |
| DOI | 10.7536/PC150437 |
| 英文摘要 | Ordered mesoporous silica nanoparticles (MSNs) have drawn a great deal of attention in the biomedical fields because of their specific structures and unique physical chemistry properties. Combined with various functional materials or molecules, such as magnetic nanoparticles, fluorescent probes, antineoplastic drugs and targeting ligands, ordered mesoporous silica nanoparticles can be developed into the multifunctional nanomedicines in the application of diagnosis and therapy of tumor. The recent progress on synthetic methods, surface modification and application of MSNs are reviewed. First of all, the methods of synthesis in different pH medium and template removal are summarized in detail along with a brief introduction on their merits and drawbacks. Secondly, surface modification methods are described, including surface stabilization and surface functionalization. Thirdly, the application progress of targeted therapy and imaging diagnosis of MSNs loaded with imaging agents or chemotherapy drugs are also concluded. The final part outlines the challenges and perspectives. |
| 资助项目 | [National Natural Science Foundation of China] ; [Chinese Postdoctoral Science Foundation] |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/284082]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.中国科学院上海药物研究所 2.广州中医药大学 |
| 推荐引用方式 GB/T 7714 | Ceng F,Pan ZZ,Zhang M,et al. preparationandapplicationoforderedmesoporoussilicananoparticlesinthetherapyanddiagnosisoftumor[J]. progressinchemistry,2015,27(10):1356. |
| APA | 曾峰,潘真真,张梦,黄永焯,崔彦娜,&徐勤.(2015).preparationandapplicationoforderedmesoporoussilicananoparticlesinthetherapyanddiagnosisoftumor.progressinchemistry,27(10),1356. |
| MLA | 曾峰,et al."preparationandapplicationoforderedmesoporoussilicananoparticlesinthetherapyanddiagnosisoftumor".progressinchemistry 27.10(2015):1356. |
入库方式： OAI收割
来源：上海药物研究所
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