sulfatedpolymannuroguluronateinhibitstatinducedslkcelladhesionviaanovelbindingsiteakkrspatialtriad
文献类型：期刊论文
| 作者 | Wu Yanlin1; Ai Jing2 ; Zhao Jingming3; Xiong Bing2; Xin Xiaojie2; Geng Meiyu2; Xin Xianliang2; Jiang Handong3
|
| 刊名 | actapharmacologicasinica
 |
| 出版日期 | 2011 |
| 卷号 | 32期号:5页码:647 |
| 关键词 | HIV-1 TAT PROTEIN INTERACTIONS HEPARAN-SULFATE KAPOSIS-SARCOMA DRUG CANDIDATE GROWTH-FACTOR DOMAIN OLIGOSACCHARIDES MULTIPLE SIZE sulfated polymannuroguluronate transactivating factor of the HIV-1 virus (Tat) binding site Kaposi's sarcoma heparin mutation HIV-1 |
| ISSN号 | 1671-4083 |
| DOI | 10.1038/aps.2011.2 |
| 英文摘要 | Aim: Sulfated polymannuroguluronate (SPMG), a candidate anti-AIDS drug, inhibited HIV replication and interfered with HIV entry into host T lymphocytes. SPMG has high binding affinity for the transactivating factor of the HIV-1 virus (Tat) via its basic domain. However, deletion or substitution of the basic domain affected, but did not completely eliminated Tat-SPMG interactions. Here, we sought to identify other SPMG binding sites in addition to the basic domain. |
| 资助项目 | [National Natural Science Foundation of China] |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/284602]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.中国海洋大学 2.中国科学院上海药物研究所 3.青岛大学 |
| 推荐引用方式 GB/T 7714 | Wu Yanlin,Ai Jing,Zhao Jingming,et al. sulfatedpolymannuroguluronateinhibitstatinducedslkcelladhesionviaanovelbindingsiteakkrspatialtriad[J]. actapharmacologicasinica,2011,32(5):647. |
| APA | Wu Yanlin.,Ai Jing.,Zhao Jingming.,Xiong Bing.,Xin Xiaojie.,...&Jiang Handong.(2011).sulfatedpolymannuroguluronateinhibitstatinducedslkcelladhesionviaanovelbindingsiteakkrspatialtriad.actapharmacologicasinica,32(5),647. |
| MLA | Wu Yanlin,et al."sulfatedpolymannuroguluronateinhibitstatinducedslkcelladhesionviaanovelbindingsiteakkrspatialtriad".actapharmacologicasinica 32.5(2011):647. |
入库方式： OAI收割
来源：上海药物研究所
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