蛋白磷酸酶2a的结构功能和活性调节
文献类型：期刊论文
| 作者 | 刘卫军; 沈瑛; 丁健
|
| 刊名 | 生物化学与生物物理学报
 |
| 出版日期 | 2003 |
| 卷号 | 35期号:2页码:105 |
| 关键词 | CATALYTIC SUBUNIT BCL2 PHOSPHORYLATION SIGNAL-TRANSDUCTION DNA-REPLICATION C-ALPHA BINDING FAMILY CANCER PP2A DEPHOSPHORYLATION protein phosphatase 2A(PP2A) holoenzyme complex core dimer enzyme |
| ISSN号 | 0582-9879 |
| 英文摘要 | Protein phosphatase 2A ( PP2A) is a major kind of serine/threonine protein phosphatase in eukaryotic cells. PP2A has many subunits and isozymes encoded by different genes to form many different PP2A holo-enzymes. PP2A play important roles in regulation of cell cycle, signal transduction, cell differentiation, and transformation. Its activity is related to several diseases, including neurodegenerative diseases and cancer. The regulation of PP2A activity is accomplished by its subunits' expression, cellular localization, phosphorylation and methylation. The second messenger, ceramide, also plays an important role in the regulation of PP2A activity, as well as a plenty of low molecular mass inhibitors of PP2A and other protein phosphatases. |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/285245]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 中国科学院上海药物研究所 |
| 推荐引用方式 GB/T 7714 | 刘卫军,沈瑛,丁健. 蛋白磷酸酶2a的结构功能和活性调节[J]. 生物化学与生物物理学报,2003,35(2):105. |
| APA | 刘卫军,沈瑛,&丁健.(2003).蛋白磷酸酶2a的结构功能和活性调节.生物化学与生物物理学报,35(2),105. |
| MLA | 刘卫军,et al."蛋白磷酸酶2a的结构功能和活性调节".生物化学与生物物理学报 35.2(2003):105. |
入库方式： OAI收割
来源：上海药物研究所
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