isomerselectivedistributionof3nbutylphthalidenbphydroxylatedmetabolites3hydroxynbpand10hydroxynbpacrosstheratbloodbrainbarrier
文献类型：期刊论文
| 作者 | Diao Xingxing; Zhong Kan; Li Xiuli; Zhong Dafang ; Chen Xiaoyan
|
| 刊名 | actapharmacologicasinica
 |
| 出版日期 | 2015 |
| 卷号 | 36期号:12页码:1520 |
| 关键词 | CANCER RESISTANCE PROTEIN P-GLYCOPROTEIN P-GP/ABCB1 TANDEM MASS-SPECTROMETRY FOCAL CEREBRAL-ISCHEMIA PLASMA-PROTEIN CHIRAL 3-N-BUTYLPHTHALIDE TISSUE DISTRIBUTION DRUG DISCOVERY BINDING PENETRATION 3-n-butylphthalide (NBP) 3-OH-NBP 10-OH-NBP blood-brain barrier isomer-selective drug plasma protein binding drug brain protein binding P-gp/BCRP cerebral ischemia |
| ISSN号 | 1671-4083 |
| DOI | 10.1038/aps.2015.64 |
| 英文摘要 | Aim: To investigate the mechanisms underlying the isomer-selective distribution of 3-n-butylphthalide (NBP) hydroxylated metabolites, 3-hydroxy-NBP (3-OH-NBP) and 10-hydroxy-NBP (10-OH-NBP), across the blood brain barrier (BBB). |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/285471]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 中国科学院上海药物研究所 |
| 推荐引用方式 GB/T 7714 | Diao Xingxing,Zhong Kan,Li Xiuli,et al. isomerselectivedistributionof3nbutylphthalidenbphydroxylatedmetabolites3hydroxynbpand10hydroxynbpacrosstheratbloodbrainbarrier[J]. actapharmacologicasinica,2015,36(12):1520. |
| APA | Diao Xingxing,Zhong Kan,Li Xiuli,Zhong Dafang,&Chen Xiaoyan.(2015).isomerselectivedistributionof3nbutylphthalidenbphydroxylatedmetabolites3hydroxynbpand10hydroxynbpacrosstheratbloodbrainbarrier.actapharmacologicasinica,36(12),1520. |
| MLA | Diao Xingxing,et al."isomerselectivedistributionof3nbutylphthalidenbphydroxylatedmetabolites3hydroxynbpand10hydroxynbpacrosstheratbloodbrainbarrier".actapharmacologicasinica 36.12(2015):1520. |
入库方式： OAI收割
来源：上海药物研究所
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