电场驱动微悬臂生物传感器及对dna的快速高灵敏度检测
文献类型：期刊论文
| 作者 | Zhang ZX; Li MQ |
| 刊名 | 生物化学与生物物理进展
 |
| 出版日期 | 2005 |
| 卷号 | 32期号:4页码:314 |
| 关键词 | RESONANCE-FREQUENCY CANTILEVER ARRAY MICROARRAYS TECHNOLOGY microcantilever biosensor electrostatic field sensitivity |
| ISSN号 | 1000-3282 |
| 英文摘要 | Microcantilever array biosensor shows peculiarities of high speed, trace detection and label-free in bioanalysis. A method to increase the detection sensitivity and to speed up analysis of microcantilever array biosensor is reported. The gold covered microcantilever array immobilized by DNA probes is applied as a microcantilever array biosensor with electrostatic field. Microcantilever arry is acted as anode in hybridization solution cell where DNA molecules are removed to and congregated around anode, so the DNA hybridization is enhanced. The data demonstrated: (1) the time of DNA hybridization on the cantilever system drived by direct electric field was no more than 3 min; (2) the detection sensitivity was improved from 30 mu g/L to 300 ng/L level. |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/285671]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 中国科学院上海药物研究所 |
| 推荐引用方式 GB/T 7714 | Zhang ZX,Li MQ. 电场驱动微悬臂生物传感器及对dna的快速高灵敏度检测[J]. 生物化学与生物物理进展,2005,32(4):314. |
| APA | Zhang ZX,&Li MQ.(2005).电场驱动微悬臂生物传感器及对dna的快速高灵敏度检测.生物化学与生物物理进展,32(4),314. |
| MLA | Zhang ZX,et al."电场驱动微悬臂生物传感器及对dna的快速高灵敏度检测".生物化学与生物物理进展 32.4(2005):314. |
入库方式： OAI收割
来源：上海药物研究所
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