中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
phaseistudyonthepharmacokineticsandtoleranceofzt1aprodrugofhuperzineaforthetreatmentofalzheimersdisease

文献类型:期刊论文

作者Jia Jingying2; Zhao Qianhua1; Liu Yun2; Gui Yuzhou3; Liu Gangyi2; Zhu Dayuan3; Yu Chen2; Hong Zhen1
刊名actapharmacologicasinica
出版日期2013
卷号34期号:7页码:976
ISSN号1671-4083
关键词CHOLINESTERASE INHIBITOR CHOLINERGIC HYPOTHESIS PROGRESS RAT MEDICINE VITRO DRUG ZT-1 huperzine A prodrug AChE inhibitor drug tolerance pharmacokinetics Alzheimer's disease
DOI10.1038/aps.2013.7
英文摘要Aim: Huperzine A isolated from the Chinese herb Huperzia serrata (Thunb) Trev is a novel reversible and selective AChE inhibitor. The aim of this study was to evaluate the pharmacokinetics and tolerance of single and multiple doses of ZT-1, a novel analogue of huperzine A, in healthy Chinese subjects.
语种英语
源URL[http://119.78.100.183/handle/2S10ELR8/287078]  
专题中国科学院上海药物研究所
作者单位1.复旦大学
2.Central Laboratory, Shanghai Xuhui Central Hospital
3.中国科学院上海药物研究所
推荐引用方式
GB/T 7714
Jia Jingying,Zhao Qianhua,Liu Yun,et al. phaseistudyonthepharmacokineticsandtoleranceofzt1aprodrugofhuperzineaforthetreatmentofalzheimersdisease[J]. actapharmacologicasinica,2013,34(7):976.
APA Jia Jingying.,Zhao Qianhua.,Liu Yun.,Gui Yuzhou.,Liu Gangyi.,...&Hong Zhen.(2013).phaseistudyonthepharmacokineticsandtoleranceofzt1aprodrugofhuperzineaforthetreatmentofalzheimersdisease.actapharmacologicasinica,34(7),976.
MLA Jia Jingying,et al."phaseistudyonthepharmacokineticsandtoleranceofzt1aprodrugofhuperzineaforthetreatmentofalzheimersdisease".actapharmacologicasinica 34.7(2013):976.

入库方式: OAI收割

来源:上海药物研究所

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