phaseistudyonthepharmacokineticsandtoleranceofzt1aprodrugofhuperzineaforthetreatmentofalzheimersdisease
文献类型：期刊论文
| 作者 | Jia Jingying2; Zhao Qianhua1; Liu Yun2; Gui Yuzhou3; Liu Gangyi2; Zhu Dayuan3; Yu Chen2; Hong Zhen1 |
| 刊名 | actapharmacologicasinica
 |
| 出版日期 | 2013 |
| 卷号 | 34期号:7页码:976 |
| 关键词 | CHOLINESTERASE INHIBITOR CHOLINERGIC HYPOTHESIS PROGRESS RAT MEDICINE VITRO DRUG ZT-1 huperzine A prodrug AChE inhibitor drug tolerance pharmacokinetics Alzheimer's disease |
| ISSN号 | 1671-4083 |
| DOI | 10.1038/aps.2013.7 |
| 英文摘要 | Aim: Huperzine A isolated from the Chinese herb Huperzia serrata (Thunb) Trev is a novel reversible and selective AChE inhibitor. The aim of this study was to evaluate the pharmacokinetics and tolerance of single and multiple doses of ZT-1, a novel analogue of huperzine A, in healthy Chinese subjects. |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/287078]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.复旦大学 2.Central Laboratory, Shanghai Xuhui Central Hospital 3.中国科学院上海药物研究所 |
| 推荐引用方式 GB/T 7714 | Jia Jingying,Zhao Qianhua,Liu Yun,et al. phaseistudyonthepharmacokineticsandtoleranceofzt1aprodrugofhuperzineaforthetreatmentofalzheimersdisease[J]. actapharmacologicasinica,2013,34(7):976. |
| APA | Jia Jingying.,Zhao Qianhua.,Liu Yun.,Gui Yuzhou.,Liu Gangyi.,...&Hong Zhen.(2013).phaseistudyonthepharmacokineticsandtoleranceofzt1aprodrugofhuperzineaforthetreatmentofalzheimersdisease.actapharmacologicasinica,34(7),976. |
| MLA | Jia Jingying,et al."phaseistudyonthepharmacokineticsandtoleranceofzt1aprodrugofhuperzineaforthetreatmentofalzheimersdisease".actapharmacologicasinica 34.7(2013):976. |
入库方式： OAI收割
来源：上海药物研究所
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