中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
serumandglucocorticoidinducibleproteinkinasessgksapotentialtargetforcancerintervention

文献类型:期刊论文

作者Basnet Rajesh; Gong Grace Qun; Li Chenyao; Wang Mingwei
刊名actapharmaceuticasinicab
出版日期2018
卷号000期号:005页码:767
关键词SGK AKT PI3K Cancer Signalling Kinase Inhibitor
ISSN号2211-3835
英文摘要The serum and glucocorticoid inducible protein kinase(SGK) family members share similar structure, substrate specificity and function with AKT and signal downstream of the phosphatidylinositol 3-kinase(PI3K) signalling pathway. They regulate a range of fundamental cellular processes such as cell proliferation and survival, thereby playing an important role in cancer development. This perspective intends to give an overview on the involvement of SGKs(particularly SGK3) in cancer progression, and compares the actions of SGK3 and AKT in cell cycle regulation, oncogenic signalling, and the potential as a therapeutic target for cancer.
语种英语
源URL[http://119.78.100.183/handle/2S10ELR8/287174]  
专题中国科学院上海药物研究所
作者单位中国科学院上海药物研究所
推荐引用方式
GB/T 7714
Basnet Rajesh,Gong Grace Qun,Li Chenyao,et al. serumandglucocorticoidinducibleproteinkinasessgksapotentialtargetforcancerintervention[J]. actapharmaceuticasinicab,2018,000(005):767.
APA Basnet Rajesh,Gong Grace Qun,Li Chenyao,&Wang Mingwei.(2018).serumandglucocorticoidinducibleproteinkinasessgksapotentialtargetforcancerintervention.actapharmaceuticasinicab,000(005),767.
MLA Basnet Rajesh,et al."serumandglucocorticoidinducibleproteinkinasessgksapotentialtargetforcancerintervention".actapharmaceuticasinicab 000.005(2018):767.

入库方式: OAI收割

来源:上海药物研究所

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