serumandglucocorticoidinducibleproteinkinasessgksapotentialtargetforcancerintervention
文献类型：期刊论文
| 作者 | Basnet Rajesh; Gong Grace Qun; Li Chenyao; Wang Mingwei
|
| 刊名 | actapharmaceuticasinicab
 |
| 出版日期 | 2018 |
| 卷号 | 000期号:005页码:767 |
| 关键词 | SGK AKT PI3K Cancer Signalling Kinase Inhibitor |
| ISSN号 | 2211-3835 |
| 英文摘要 | The serum and glucocorticoid inducible protein kinase(SGK) family members share similar structure, substrate specificity and function with AKT and signal downstream of the phosphatidylinositol 3-kinase(PI3K) signalling pathway. They regulate a range of fundamental cellular processes such as cell proliferation and survival, thereby playing an important role in cancer development. This perspective intends to give an overview on the involvement of SGKs(particularly SGK3) in cancer progression, and compares the actions of SGK3 and AKT in cell cycle regulation, oncogenic signalling, and the potential as a therapeutic target for cancer. |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/287174]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 中国科学院上海药物研究所 |
| 推荐引用方式 GB/T 7714 | Basnet Rajesh,Gong Grace Qun,Li Chenyao,et al. serumandglucocorticoidinducibleproteinkinasessgksapotentialtargetforcancerintervention[J]. actapharmaceuticasinicab,2018,000(005):767. |
| APA | Basnet Rajesh,Gong Grace Qun,Li Chenyao,&Wang Mingwei.(2018).serumandglucocorticoidinducibleproteinkinasessgksapotentialtargetforcancerintervention.actapharmaceuticasinicab,000(005),767. |
| MLA | Basnet Rajesh,et al."serumandglucocorticoidinducibleproteinkinasessgksapotentialtargetforcancerintervention".actapharmaceuticasinicab 000.005(2018):767. |
入库方式： OAI收割
来源：上海药物研究所
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