mhcn1通道孔隙多肽溶液构象的核磁共振研究
文献类型：期刊论文
| 作者 | 眭涛1; 俞汉钢2; 胡红雨3; 施燕红1 ; 宋国强1
|
| 刊名 | 生物化学与生物物理学报
 |
| 出版日期 | 2003 |
| 卷号 | 35期号:1页码:59 |
| 关键词 | POTASSIUM mHCN1 pore peptide NMR solution structure |
| ISSN号 | 0582-9879 |
| 英文摘要 | Spin systems for amino acid residues in mHCN1 pore region peptide have been identified through analysis of 2D NMR spectra. The sequence-specific assignment of spin systems was obtained by NOEs correlation in WET-NOESY spectra, and the complete assignment of proton resonances for backbone and side chain has been achieved. CNS software was used to calculate the structure of mHCN1 19 aa peptide. The results show that an alpha-helix from residue 10 to residue 13 is formed within the pore region. The results of NMR study on mHCN1 pore peptide provide the basis for further understanding the mechanism of ion selectivity of channels. |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/287808]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.中国科学院上海药物研究所 2.纽约科技学院 3.中国科学院上海生命科学研究院 |
| 推荐引用方式 GB/T 7714 | 眭涛,俞汉钢,胡红雨,等. mhcn1通道孔隙多肽溶液构象的核磁共振研究[J]. 生物化学与生物物理学报,2003,35(1):59. |
| APA | 眭涛,俞汉钢,胡红雨,施燕红,&宋国强.(2003).mhcn1通道孔隙多肽溶液构象的核磁共振研究.生物化学与生物物理学报,35(1),59. |
| MLA | 眭涛,et al."mhcn1通道孔隙多肽溶液构象的核磁共振研究".生物化学与生物物理学报 35.1(2003):59. |
入库方式： OAI收割
来源：上海药物研究所
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