enhancementofcellularuptaketransportandoralabsorptionofproteaseinhibitorsaquinavirbynanocrystalformulation
文献类型：期刊论文
| 作者 | He Yuan1; Xia Dengning2; Li Qiuxia1; Tao Jinsong2; Gan Yong2 ; Wang Chi1
|
| 刊名 | actapharmacologicasinica
 |
| 出版日期 | 2015 |
| 卷号 | 36期号:9页码:1151 |
| 关键词 | NITRENDIPINE NANOCRYSTALS P-GLYCOPROTEIN NANOPARTICLES BIOAVAILABILITY CELLS STABILITY DELIVERY DRUGS FATE saquinavir protease inhibitor nanocrystals Caco-2 cell monolayer intestinal mucosa pharmacokinetics |
| ISSN号 | 1671-4083 |
| DOI | 10.1038/aps.2015.53 |
| 英文摘要 | Aim: Saquinavir (SQV) is the first protease inhibitor for the treatment of HIV infection, but with poor solubility. The aim of this study was to prepare a colloidal nanocrystal suspension for improving the oral absorption of SQV. |
| 资助项目 | [National Natural Science Foundations of China] ; [China Postdoctoral Science Foundations] ; [Shanghai Science and Technology Innovation Action Plan for Basic Research] ; [SA-SIBS scholarship program] |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/288134]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.重庆医科大学 2.中国科学院上海药物研究所 |
| 推荐引用方式 GB/T 7714 | He Yuan,Xia Dengning,Li Qiuxia,et al. enhancementofcellularuptaketransportandoralabsorptionofproteaseinhibitorsaquinavirbynanocrystalformulation[J]. actapharmacologicasinica,2015,36(9):1151. |
| APA | He Yuan,Xia Dengning,Li Qiuxia,Tao Jinsong,Gan Yong,&Wang Chi.(2015).enhancementofcellularuptaketransportandoralabsorptionofproteaseinhibitorsaquinavirbynanocrystalformulation.actapharmacologicasinica,36(9),1151. |
| MLA | He Yuan,et al."enhancementofcellularuptaketransportandoralabsorptionofproteaseinhibitorsaquinavirbynanocrystalformulation".actapharmacologicasinica 36.9(2015):1151. |
入库方式： OAI收割
来源：上海药物研究所
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