Selective Late-Stage Oxygenation of Sulfides with Ground-State Oxygen by Uranyl Photocatalysis
文献类型：期刊论文
| 作者 | Li, Yiming1; Rizvi, S. Aal-e-Ali1; Hu, Deqing1; Sun, Danwen1; Gao, Anhui3; Zhou, Yubo3 ; Li, Jia1,3; Jiang, Xuefeng1,2
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| 刊名 | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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| 出版日期 | 2019-08-08 |
| 页码 | 9 |
| 关键词 | oxygen oxygenation photocatalysis sulfides uranyl catalysis |
| ISSN号 | 1433-7851 |
| DOI | 10.1002/anie.201906080 |
| 通讯作者 | Jiang, Xuefeng(xfjiang@chem.ecnu.edu.cn) |
| 英文摘要 | Oxygenation is a fundamental transformation in synthesis. Herein, we describe the selective late-stage oxygenation of sulfur-containing complex molecules with ground-state oxygen under ambient conditions. The high oxidation potential of the active uranyl cation (UO22+) enabled the efficient synthesis of sulfones. The ligand-to-metal charge transfer process (LMCT) from O 2p to U 5f within the O=U=O group, which generates a U-V center and an oxygen radical, is assumed to be affected by the solvent and additives, and can be tuned to promote selective sulfoxidation. This tunable strategy enabled the batch synthesis of 32 pharmaceuticals and analogues by late-stage oxygenation in an atom- and step-efficient manner. |
| WOS关键词 | PHOTOREDOX-CATALYSIS ; PHOTOCHEMICAL ACTIVITY ; ALPHA-ALKYLATION ; SINGLET-OXYGEN ; ELECTRON ; OXIDATION ; PHOTOOXIDATION ; SULFOXIDES ; REDUCTION ; MECHANISM |
| 资助项目 | National Key Research and Development Program of China[2017YFD0200500] ; NSFC[21722202] ; NSFC[21672069] ; NSFC[21472050] ; S&TCSM of Shanghai[18JC1415600] ; Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning ; National Program for Support of Top-notch Young Professionals ; China Postdoctoral Science Foundation[2018M632059] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000480984700001 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/288877]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Jiang, Xuefeng |
| 作者单位 | 1.East China Normal Univ, Dept Chem, Shanghai Key Lab Green Chem & Chem Proc, 3663 North Zhongshan Rd, Shanghai 200062, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, Lab Drug Res, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Yiming,Rizvi, S. Aal-e-Ali,Hu, Deqing,et al. Selective Late-Stage Oxygenation of Sulfides with Ground-State Oxygen by Uranyl Photocatalysis[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2019:9. |
| APA | Li, Yiming.,Rizvi, S. Aal-e-Ali.,Hu, Deqing.,Sun, Danwen.,Gao, Anhui.,...&Jiang, Xuefeng.(2019).Selective Late-Stage Oxygenation of Sulfides with Ground-State Oxygen by Uranyl Photocatalysis.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,9. |
| MLA | Li, Yiming,et al."Selective Late-Stage Oxygenation of Sulfides with Ground-State Oxygen by Uranyl Photocatalysis".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019):9. |
入库方式： OAI收割
来源：上海药物研究所
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