A galactoglucan isolated from of Cistanche deserticola Y. C. Ma. and its bioactivity on intestinal bacteria strains
文献类型：期刊论文
| 作者 | Zeng, Hui1,2; Huang, Lulin1,2; Zhou, Lishuang1,2; Wang, Peipei1,2 ; Chen, Xia1,2; Ding, Kan1,2
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| 刊名 | CARBOHYDRATE POLYMERS
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| 出版日期 | 2019-11-01 |
| 卷号 | 223页码:8 |
| 关键词 | Cistanche deserticola Polysaccharide Structure Intestinal flora |
| ISSN号 | 0144-8617 |
| DOI | 10.1016/j.carbpol.2019.115038 |
| 通讯作者 | Ding, Kan(dingkan@simm.ac.cn) |
| 英文摘要 | To understand whether polysaccharides may have impact on gut microbiota, a neutral polysaccharide CDA-0.05 with an average molecular weight of 7.96 kDa was obtained from Cistanche deserticola Y. C. Ma. The monosaccharide composition analysis indicated that CDA-0.05 was composed of glucose and galactose in a molar ratio of 96.4: 3.6. The backbone of CDA-0.05 contained 1, 4-linked alpha-D-Glcp, 1, 4, 6-linked alpha-D-Glcp and 1, 4-linked beta-D-Galp, with branches of T-linked alpha-D-Glcp attached at C-6 of 1, 4, 6-linked alpha-D-Glcp residues. Bioactivity test results suggested that CDA-0.05 could promote the growth of three species of Bacteroides (B. thetaiotaomicron, B. ovatus and B. fragilis) significantly. Furthermore, CDA-0.05 could also promote some probiotics growth, such as Lactobacillus casei, Lactobacillus plantarum and Lactobacillus reuteri. These results suggested that CDA-0.05 might help to maintain intestinal homeostasis and could be recommended as part of fibers or drugs candidate to benefit human body by regulating gut bacteria. |
| WOS关键词 | HUMAN GUT SYMBIONT ; CHAIN FATTY-ACIDS ; STRUCTURAL-CHARACTERIZATION ; BACTEROIDES-THETAIOTAOMICRON ; POLYSACCHARIDE ; MICROBIOTA ; ELUCIDATION ; METABOLITE ; FUCOIDAN ; FLOWERS |
| 资助项目 | National Natural Science Foundation of China (NSFC)[31670814] ; Program of Shanghai Subject Chief Scientist[16XD1404500] |
| WOS研究方向 | Chemistry ; Polymer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000481570700002 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/288975]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Ding, Kan |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Key Lab Receptor Res, Glycochem & Glycobiol Lab, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China 2.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zeng, Hui,Huang, Lulin,Zhou, Lishuang,et al. A galactoglucan isolated from of Cistanche deserticola Y. C. Ma. and its bioactivity on intestinal bacteria strains[J]. CARBOHYDRATE POLYMERS,2019,223:8. |
| APA | Zeng, Hui,Huang, Lulin,Zhou, Lishuang,Wang, Peipei,Chen, Xia,&Ding, Kan.(2019).A galactoglucan isolated from of Cistanche deserticola Y. C. Ma. and its bioactivity on intestinal bacteria strains.CARBOHYDRATE POLYMERS,223,8. |
| MLA | Zeng, Hui,et al."A galactoglucan isolated from of Cistanche deserticola Y. C. Ma. and its bioactivity on intestinal bacteria strains".CARBOHYDRATE POLYMERS 223(2019):8. |
入库方式： OAI收割
来源：上海药物研究所
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