中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
A review on analytical methods for natural berberine alkaloids

文献类型:期刊论文

作者Wang, Jiahui1; Jiang, Yanyan2; Wang, Bing3,4; Zhang, Ning1
刊名JOURNAL OF SEPARATION SCIENCE
出版日期2019-05-01
卷号42期号:9页码:1794-1815
关键词berberine alkaloids gas chromatography liquid chromatography mass spectrometry thin-layer chromatography
ISSN号1615-9306
DOI10.1002/jssc.201800952
通讯作者Wang, Bing(bwang@simm.ac.cn) ; Zhang, Ning(ningzh18@126.com)
英文摘要Berberine alkaloids, a group of protoberberine alkaloids under the classification of isoquinoline alkaloids, include berberine, coptisine, palmatine, columbamine, dehydrocorydaline, jatrorrhizine, and epiberberine from natural sources. Studies have shown that berberine alkaloids have various pharmacological functions, such as antibacterial, antiviral, blood pressure-lowering, hypoglycaemic, antiarrhythmia, and anticancer effects. Therefore, it is worthwhile to develop analytical methods to investigate the pharmacokinetics and activity mechanisms of berberine alkaloids and to study berberine alkaloids more comprehensively. Current analytical methods for berberine alkaloids include liquid chromatography, thin-layer chromatography, ultraviolet spectroscopy, capillary electrophoresis, and gas chromatography. The most widely used detection method is mass spectrometry. In order to provide a systematic and comprehensive summary and to serve as a reference for the future pharmacokinetics studies and analysis of berberine alkaloids, analytical methods for natural berberine alkaloids that have been used in the past ten years are reviewed here.
WOS关键词PERFORMANCE LIQUID-CHROMATOGRAPHY ; TANDEM MASS-SPECTROMETRY ; TRADITIONAL CHINESE MEDICINE ; PROCESSED RHIZOMA-COPTIDIS ; RAT PLASMA APPLICATION ; UPLC-MS/MS METHOD ; DRUG PHARMACOKINETIC INTERACTION ; MAJOR BIOACTIVE COMPONENTS ; TYPE-2 DIABETIC-RATS ; SI-WU DECOCTION
资助项目Shanghai Committee of Science and Technology[17401902300]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000471322300004
出版者WILEY-V C H VERLAG GMBH
源URL[http://119.78.100.183/handle/2S10ELR8/289443]  
专题中国科学院上海药物研究所
通讯作者Wang, Bing; Zhang, Ning
作者单位1.Shanghai Univ Tradit Chinese Med, Expt Ctr Sci & Technol, Shanghai, Peoples R China
2.Fudan Univ, Key Lab Smart Drug Delivery, Minist Educ & PLA, Dept Pharmaceut,Sch Pharm, Shanghai, Peoples R China
3.Shanghai Univ Tradit Chinese Med, Sch Pharm, 1200 Cai lun Rd, Shanghai 201203, Peoples R China
4.Chinese Acad Sci, Shanghai Inst Materia Med, Shanghai, Peoples R China
推荐引用方式
GB/T 7714
Wang, Jiahui,Jiang, Yanyan,Wang, Bing,et al. A review on analytical methods for natural berberine alkaloids[J]. JOURNAL OF SEPARATION SCIENCE,2019,42(9):1794-1815.
APA Wang, Jiahui,Jiang, Yanyan,Wang, Bing,&Zhang, Ning.(2019).A review on analytical methods for natural berberine alkaloids.JOURNAL OF SEPARATION SCIENCE,42(9),1794-1815.
MLA Wang, Jiahui,et al."A review on analytical methods for natural berberine alkaloids".JOURNAL OF SEPARATION SCIENCE 42.9(2019):1794-1815.

入库方式: OAI收割

来源:上海药物研究所

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