Quantitative Analysis of Artemisinin Derivatives: Applications and Techniques
文献类型：期刊论文
| 作者 | Zhang, Lili1; Jiang, Yanyan3; Li, Ning4; Pu, Yiqiong2; Zhang, Tong1,2; Wang, Bing1,5 |
| 刊名 | SEPARATION AND PURIFICATION REVIEWS
 |
| 出版日期 | 2019-07-03 |
| 卷号 | 48期号:3页码:242-266 |
| 关键词 | Artemisinin derivatives quantitative analysis spectroscopy chromatography mass spectrometry |
| ISSN号 | 1542-2119 |
| DOI | 10.1080/15422119.2018.1560331 |
| 通讯作者 | Zhang, Tong(zhangtdmj@hotmail.com) ; Wang, Bing(bwang@simm.ac.cn) |
| 英文摘要 | Research on artemisinin and its derivatives (ARTDs) were initiated due to their outstanding anti-malarial effects. In the past few decades, considerable efforts have been made to extend the clinical applications of ARTDs. However, some ARTDs have a low aqueous solubility, short half-life in vivo and instability due to an endoperoxide bridge in their structures that also contributes to a poor bioavailability. The development of efficient quantitative analysis methods is needed for many branches of research, such as the chemical compound determination in plants, drug quality control and drug metabolism studies. The analysis methods used to detect ARTDs include spectroscopy, liquid chromatography, mass spectrometry and immunoassays. However, a systematic quantitative analysis of these compounds as the very first step in many studies has not been always conducted. Thus, this review presents a comprehensive overview of available analytical methods for in vivo and in vitro quantitation of ARTDs. It generalizes and compares the various methods focusing on sample preparation. |
| WOS关键词 | PERFORMANCE LIQUID-CHROMATOGRAPHY ; MASS-SPECTROMETRY METHOD ; PLASMODIUM-FALCIPARUM MALARIA ; DRUG-DELIVERY-SYSTEM ; LC-MS/MS METHOD ; ASSEMBLED BIOTRANSESTERIFIED CYCLODEXTRINS ; NANOSTRUCTURED LIPID CARRIERS ; NEW-GUINEAN CHILDREN ; IN-VITRO ; METABOLITE DIHYDROARTEMISININ |
| 资助项目 | Program of Shanghai Committee of Science and Technology[17401902300] ; Program of Shanghai Academic/Technology Research Leader[18XD1403700] ; National Scientific and Technological Major Special Project of China[2018ZX09201008-002] ; Innovation/Entrepreneurship Project of Shanghai University of Traditional Chinese Medicine[Y201857] |
| WOS研究方向 | Chemistry ; Engineering |
| 语种 | 英语 |
| WOS记录号 | WOS:000472543800003 |
| 出版者 | TAYLOR & FRANCIS INC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/289486]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Zhang, Tong; Wang, Bing |
| 作者单位 | 1.Shanghai Univ Tradit Chinese Med, Sch Pharm, Shanghai, Peoples R China 2.Shanghai Univ Tradit Chinese Med, Expt Ctr Teaching & Learning, Shanghai, Peoples R China 3.Fudan Univ, Sch Pharm, Dept Pharmaceut, Key Lab Smart Drug Delivery,Minist Educ & PLA, Shanghai, Peoples R China 4.Shanghai Univ Tradit Chinese Med, Inst Chinese Mat Med, Shanghai, Peoples R China 5.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Lili,Jiang, Yanyan,Li, Ning,et al. Quantitative Analysis of Artemisinin Derivatives: Applications and Techniques[J]. SEPARATION AND PURIFICATION REVIEWS,2019,48(3):242-266. |
| APA | Zhang, Lili,Jiang, Yanyan,Li, Ning,Pu, Yiqiong,Zhang, Tong,&Wang, Bing.(2019).Quantitative Analysis of Artemisinin Derivatives: Applications and Techniques.SEPARATION AND PURIFICATION REVIEWS,48(3),242-266. |
| MLA | Zhang, Lili,et al."Quantitative Analysis of Artemisinin Derivatives: Applications and Techniques".SEPARATION AND PURIFICATION REVIEWS 48.3(2019):242-266. |
入库方式： OAI收割
来源：上海药物研究所
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