Profiling of Histidine Phosphoproteome in Danio rerio by TiO2 Enrichment
文献类型：期刊论文
| 作者 | Gao, Yan1,2; Lee, Hyojin3,4; Kwon, Oh Kwang1,2; Cheng, Zhongyi5; Tan, Minjia6 ; Kim, Ki-Tae3,4; Lee, Sangkyu1,2
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| 刊名 | PROTEOMICS
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| 出版日期 | 2019-05-01 |
| 卷号 | 19期号:9页码:4 |
| 关键词 | D rerio histidine phosphorylation TiO2 affinity chromatography |
| ISSN号 | 1615-9853 |
| DOI | 10.1002/pmic.201800471 |
| 通讯作者 | Kim, Ki-Tae(ktkim@seoultech.ac.kr) ; Lee, Sangkyu(sangkyu@knu.ac.kr) |
| 英文摘要 | Histidine phosphorylation is a reversible post-translational modification that is known to regulate signal transduction in prokaryotes. However, functional studies in eukaryotes have been largely neglected due to the labile nature of N-linked phosphorylated amino acids. In an effort to help elucidate the heretofore hidden vertebrate phosphoproteome, this report presents a global phosphorylation analysis of Danio rerio (zebrafish) larvae. Phosphopeptide enrichment is performed using a TiO2 affinity technique. A total of 68 unique phosphohistidine sites are detected on 63 proteins among 1076 unique phosphosites on 708 proteins. Data are available via ProteomeXchange with identifier PXD012735. This report provides the first phosphohistidine dataset obtained from zebrafish. |
| WOS关键词 | GLOBAL PROTEOMIC ANALYSIS ; PROTEIN ; PHOSPHORYLATION ; PHOSPHOHISTIDINE ; ACETYLATION ; PROKARYOTES ; RESOURCE ; KINASES |
| 资助项目 | National Research Foundation of Korea(NRF) - Korea government[NRF-2018R1D1A1A02043591] ; Korea Ministry of Environment (MOE) as the Environmental Health Action Program[2016001370001] |
| WOS研究方向 | Biochemistry & Molecular Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:000471337400002 |
| 出版者 | WILEY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/289515]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Kim, Ki-Tae; Lee, Sangkyu |
| 作者单位 | 1.Kyungpook Natl Univ, Plus KNU Multiom Based Creat Drug Res Team, Coll Pharm, BK21, Daegu 41566, South Korea 2.Kyungpook Natl Univ, Res Inst Pharmaceut Sci, Daegu 41566, South Korea 3.Seoul Natl Univ Sci & Technol, Dept Energy & Environm Engn, Seoul 01811, South Korea 4.Seoul Natl Univ Sci & Technol, Dept Environm Engn, Seoul 01811, South Korea 5.Jingjie PTM BioLab Hangzhou Co Ltd, Hangzhou 310018, Zhejiang, Peoples R China 6.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao, Yan,Lee, Hyojin,Kwon, Oh Kwang,et al. Profiling of Histidine Phosphoproteome in Danio rerio by TiO2 Enrichment[J]. PROTEOMICS,2019,19(9):4. |
| APA | Gao, Yan.,Lee, Hyojin.,Kwon, Oh Kwang.,Cheng, Zhongyi.,Tan, Minjia.,...&Lee, Sangkyu.(2019).Profiling of Histidine Phosphoproteome in Danio rerio by TiO2 Enrichment.PROTEOMICS,19(9),4. |
| MLA | Gao, Yan,et al."Profiling of Histidine Phosphoproteome in Danio rerio by TiO2 Enrichment".PROTEOMICS 19.9(2019):4. |
入库方式： OAI收割
来源：上海药物研究所
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