Structural characterization of a galactan from Dioscorea opposita Thunb. and its bioactivity on selected Bacteroides strains from human gut microbiota
文献类型：期刊论文
| 作者 | Zhang, Chun-Qian1,2,3; Chen, Xia2,3; Ding, Kan2,3
|
| 刊名 | CARBOHYDRATE POLYMERS
 |
| 出版日期 | 2019-08-15 |
| 卷号 | 218页码:299-306 |
| 关键词 | Dioscoreaopposita Thunb. Polysaccharide Galactan Human gut microbiota Short-chain fatty acids |
| ISSN号 | 0144-8617 |
| DOI | 10.1016/j.carbpol.2019.04.084 |
| 通讯作者 | Ding, Kan(dingkan@simm.ac.cn) |
| 英文摘要 | Dioscorea opposita Thunb. is widely used as functional foods and traditional Chinese medicine in China for its activity of regulating function of spleen and stomach. Polysaccharides may contribute to the function of regulation. To investigate structure features and bioactivities of polysaccharides from D. opposita, the rhizome of D. opposita was extracted with boiling water, yielding crude polysaccharides DOP. A novel polysaccharide named DOP0.1-S-1 was isolated from DOP by further purification. The average molecular weight of DOP0.1-S-1 was 10,000 Da and the range was around 12,000 -1,200 Da. The carbohydrate content of DOP0.1-S-1 was 100% and no protein was detected. The monosaccharide analysis showed that DOP0.1-S-1 was mostly composed of galactose. Methylation and NMR spectra analysis indicated that DOP0.1-S-1 was a 1,4-beta-galactan. Bioactivity test showed that DOP0.1-S-1 could promote the growth of B. thetaiotaomicron and B. ovatus and produce the short-chain fatty acids during the utilization of the polysaccharide. |
| WOS关键词 | DIETARY FIBER ; POLYSACCHARIDE ; DEGRADATION ; DIVERSITY ; STARCHES ; HEALTH |
| 资助项目 | National Natural Science Foundation of China (NSFC)[31870801] ; Program of Shanghai Subject Chief Scientist[16XD1404500] |
| WOS研究方向 | Chemistry ; Polymer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000471864400034 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/289562]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Ding, Kan |
| 作者单位 | 1.Shanghai Univ, Sch Life Sci, 333 Nanchen Rd, Shanghai 200444, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Glycochem & Glycobiol Lab, Key Lab Receptor Res, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China 3.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Chun-Qian,Chen, Xia,Ding, Kan. Structural characterization of a galactan from Dioscorea opposita Thunb. and its bioactivity on selected Bacteroides strains from human gut microbiota[J]. CARBOHYDRATE POLYMERS,2019,218:299-306. |
| APA | Zhang, Chun-Qian,Chen, Xia,&Ding, Kan.(2019).Structural characterization of a galactan from Dioscorea opposita Thunb. and its bioactivity on selected Bacteroides strains from human gut microbiota.CARBOHYDRATE POLYMERS,218,299-306. |
| MLA | Zhang, Chun-Qian,et al."Structural characterization of a galactan from Dioscorea opposita Thunb. and its bioactivity on selected Bacteroides strains from human gut microbiota".CARBOHYDRATE POLYMERS 218(2019):299-306. |
入库方式： OAI收割
来源：上海药物研究所
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