Pd-Catalyzed Site-Selective C(sp(2))-H Olefination and Alkynylation of Phenylalanine Residues in Peptides
文献类型：期刊论文
| 作者 | Zheng, Yong1; Song, Weibin2 |
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2019-05-03 |
| 卷号 | 21期号:9页码:3257-3260 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/acs.orglett.9b00987 |
| 通讯作者 | Song, Weibin(songwbolin@163.com) |
| 英文摘要 | Pd-catalyzed site-selective C(sp(2))-H olefination and alkynylation of phenylalanine residues in peptides are described. The amino acids within the peptides are used as native bidentate directing groups to facilitate C-H functionalization. This protocol would provide appealing strategies for the postsynthetic modification of peptides. |
| WOS关键词 | C-H ALKYNYLATION ; PALLADIUM(II)-CATALYZED ORTHO-OLEFINATION ; ACTIVATION ; ALKENYLATION ; ARENES ; FUTURE ; BONDS ; DIVERSIFICATION ; AMIDES ; MILD |
| 资助项目 | National Natural Science Foundation of China[81602995] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000467320000060 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/289710]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Song, Weibin |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, 501 Haike Rd, Shanghai 201203, Peoples R China 2.Nanjing Univ Chinese Med, Sch Pharm, Jiangsu Key Lab Funct Subst Chinese Med, Stake Key Lab Cultivat Base TCM Qual & Efficacy, Nanjing 210023, Jiangsu, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zheng, Yong,Song, Weibin. Pd-Catalyzed Site-Selective C(sp(2))-H Olefination and Alkynylation of Phenylalanine Residues in Peptides[J]. ORGANIC LETTERS,2019,21(9):3257-3260. |
| APA | Zheng, Yong,&Song, Weibin.(2019).Pd-Catalyzed Site-Selective C(sp(2))-H Olefination and Alkynylation of Phenylalanine Residues in Peptides.ORGANIC LETTERS,21(9),3257-3260. |
| MLA | Zheng, Yong,et al."Pd-Catalyzed Site-Selective C(sp(2))-H Olefination and Alkynylation of Phenylalanine Residues in Peptides".ORGANIC LETTERS 21.9(2019):3257-3260. |
入库方式： OAI收割
来源：上海药物研究所
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