Two new cembrane-type diterpenoids from the xisha soft coral Lemnalia flava
文献类型：期刊论文
| 作者 | Wu, Qihao2,3,4; Li, Heng1,2; Yang, Min1,2; Jia, Ai-Qun5; Tang, Wei2 ; Wang, Hong3,4; Guo, Yue-Wei2,3,4
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| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2019-04-01 |
| 卷号 | 134页码:481-484 |
| 关键词 | Soft coral Cembranoid Lemnalia flava |
| ISSN号 | 0367-326X |
| DOI | 10.1016/j.fitote.2019.03.018 |
| 通讯作者 | Wang, Hong() ; Guo, Yue-Wei(ywguo@simm.ac.cn) |
| 英文摘要 | Further chemical investigation of the South China Sea soft coral Lemnalia flava resulted in the isolation and characterization of two new cembranoids, namely, xishaflavalins G and H (1 and 2), along with three known related compounds (3-5). The structures of the new compounds were elucidated by detailed spectroscopic analysis and by the comparison of their spectroscopic data with those reported in the literature. The discovery of cembrane-type diterpenes from soft coral of the genus Lemnalia was reported for the first time. In addition, compound 5 exhibited moderate. inhibitory effects on the ConA-induced T lymphocytes and/or lipopolysaccharide (LPS)-induced B lymphocytes proliferation. |
| 资助项目 | National Key Research and Development Program of China[2018YFC0310903] ; Drug Innovation Major Project[2018ZX09711-001-001-009] ; National Natural Science Foundation of China (NSFC)[81520108028] ; National Natural Science Foundation of China (NSFC)[21672230] ; National Natural Science Foundation of China (NSFC)[81773628] ; NSFC-Shandong Joint Fund for Marine Science Research Centers[U1606403] |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000468710300061 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/289818]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Wang, Hong; Guo, Yue-Wei |
| 作者单位 | 1.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China 3.Zhejiang Univ Technol, Coll Pharmaceut Sci, Hangzhou 310014, Zhejiang, Peoples R China 4.Zhejiang Univ Technol, Collaborat Innovat Ctr Yangtze River Delta Reg Gr, Hangzhou 310014, Zhejiang, Peoples R China 5.Hainan Univ, Minist Educ, Key Lab Trop Biol Resources, State Key Lab Marine Resource Utilizat South Chin, Haikou 570228, Hainan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Qihao,Li, Heng,Yang, Min,et al. Two new cembrane-type diterpenoids from the xisha soft coral Lemnalia flava[J]. FITOTERAPIA,2019,134:481-484. |
| APA | Wu, Qihao.,Li, Heng.,Yang, Min.,Jia, Ai-Qun.,Tang, Wei.,...&Guo, Yue-Wei.(2019).Two new cembrane-type diterpenoids from the xisha soft coral Lemnalia flava.FITOTERAPIA,134,481-484. |
| MLA | Wu, Qihao,et al."Two new cembrane-type diterpenoids from the xisha soft coral Lemnalia flava".FITOTERAPIA 134(2019):481-484. |
入库方式： OAI收割
来源：上海药物研究所
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