Ni(ii)-catalyzed mono-selective ortho-arylation of unactivated aryl C-H bonds utilizing amino acids as a directing group
文献类型：期刊论文
| 作者 | Cong, Zhanqing1,2,3; Gao, Feng2,3; Liu, Hong1,2,3
|
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2019 |
| 卷号 | 9期号:19页码:10820-10824 |
| ISSN号 | 2046-2069 |
| DOI | 10.1039/c9ra00749k |
| 通讯作者 | Liu, Hong(hliu@simm.ac.cn) |
| 英文摘要 | The nickel(ii)-catalyzed ortho-arylation of unactivated C-H bonds utilizing amino acids as directing groups with aryl iodides or bromides as coupling electrophiles is described. This protocol features excellent mono-selectivity, good regioselectivity, and wide functional group tolerance. Additionally, the obtained products bearing a biaryl motif and an amino acid represent bioactive molecules with wide bioactivities. |
| WOS关键词 | BETA-C(SP(3))-H ARYLATION ; INTRAMOLECULAR AMINATION ; C(SP(2))-H BONDS ; C(SP(3))-H BONDS ; FUNCTIONALIZATION ; DERIVATIVES ; ACTIVATION ; BENZAMIDES ; 8-AMINOQUINOLINE ; THIOLATION |
| 资助项目 | National Natural Science Foundation of China[81620108027] ; National Natural Science Foundation of China[21632008] ; National Natural Science Foundation of China[81602975] ; Major Project of Chinese National Programs for Fundamental Research and Development[2015CB910304] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000465297300044 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/289940]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Liu, Hong |
| 作者单位 | 1.ShanghaiTech Univ, Sch Life Sci & Technol, 100 Haike Rd, Shanghai 201210, Peoples R China 2.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cong, Zhanqing,Gao, Feng,Liu, Hong. Ni(ii)-catalyzed mono-selective ortho-arylation of unactivated aryl C-H bonds utilizing amino acids as a directing group[J]. RSC ADVANCES,2019,9(19):10820-10824. |
| APA | Cong, Zhanqing,Gao, Feng,&Liu, Hong.(2019).Ni(ii)-catalyzed mono-selective ortho-arylation of unactivated aryl C-H bonds utilizing amino acids as a directing group.RSC ADVANCES,9(19),10820-10824. |
| MLA | Cong, Zhanqing,et al."Ni(ii)-catalyzed mono-selective ortho-arylation of unactivated aryl C-H bonds utilizing amino acids as a directing group".RSC ADVANCES 9.19(2019):10820-10824. |
入库方式： OAI收割
来源：上海药物研究所
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