Ratiometric fluorescent probe for sensing Streptococcus mutans glucosyltransferase, a key factor in the formation of dental caries
文献类型：期刊论文
| 作者 | Feng, Lei2,3; Yan, Qingsong2,4; Zhang, Baojing2; Tian, Xiangge2,4; Wang, Chao2,3; Yu, Zhenlong2; Cui, Jingnan3; Guo, Dean4 ; Ma, Xiaochi2,4; James, Tony D.1
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| 刊名 | CHEMICAL COMMUNICATIONS
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| 出版日期 | 2019-03-25 |
| 卷号 | 55期号:24页码:3548-3551 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/c9cc00440h |
| 通讯作者 | Wang, Chao(wach_edu@sina.com) ; Guo, Dean(daguo@simm.ac.cn) ; James, Tony D.(t.d.james@bath.ac.uk) |
| 英文摘要 | We report on a naphthalimide ratiometric fluorescent probe for the real-time sensing and imaging of pathogenic bacterial glucosyltransferases, which are associated with the development of dental caries. Using a high-throughput screening method, we identified that several natural polyphenols from green tea were GTFs inhibitors that could eventually lead to suitable oral treatments to prevent the development of dental caries. |
| WOS关键词 | BETA-GLUCURONIDASE ; LIVING CELLS ; ENZYME |
| 资助项目 | National Natural Science Foundation of China[81622047] ; National Natural Science Foundation of China[81872970] ; National Natural Science Foundation of China[81503240] ; State Key Laboratory of Fine Chemicals[KF1803] ; State Key Laboratory of Fine Chemicals[KF1705] ; Program for High-level Talents of Dalian City[2017RQ119] ; Royal Society |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | ROYAL SOC CHEMISTRY |
| WOS记录号 | WOS:000462654300024 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/290156]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Wang, Chao; Guo, Dean; James, Tony D. |
| 作者单位 | 1.Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England 2.Dalian Med Univ, Natl & Local Joint Engn Res Ctr Drug Dev Neurodeg, Acad Integrat Med, Coll Pharm, Dalian 116044, Peoples R China 3.Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China 4.Chinese Acad Sci, Natl Engn Lab TCM Standardizat Technol, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Feng, Lei,Yan, Qingsong,Zhang, Baojing,et al. Ratiometric fluorescent probe for sensing Streptococcus mutans glucosyltransferase, a key factor in the formation of dental caries[J]. CHEMICAL COMMUNICATIONS,2019,55(24):3548-3551. |
| APA | Feng, Lei.,Yan, Qingsong.,Zhang, Baojing.,Tian, Xiangge.,Wang, Chao.,...&James, Tony D..(2019).Ratiometric fluorescent probe for sensing Streptococcus mutans glucosyltransferase, a key factor in the formation of dental caries.CHEMICAL COMMUNICATIONS,55(24),3548-3551. |
| MLA | Feng, Lei,et al."Ratiometric fluorescent probe for sensing Streptococcus mutans glucosyltransferase, a key factor in the formation of dental caries".CHEMICAL COMMUNICATIONS 55.24(2019):3548-3551. |
入库方式： OAI收割
来源：上海药物研究所
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